Detailed information of TA system TA070696

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 253784..254328
• Replicon: chromosome
• Accession: NZ_CP018847
• Organism: Xanthomonas citri pv. citri strain LL074-4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: H8FI26
• Locus tag: BI314_RS01200
• Protein ID: WP_003487886.1
• Coordinates: 253784..254083 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: H8FI25
• Locus tag: BI314_RS01205
• Protein ID: WP_003487884.1
• Coordinates: 254071..254328 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BI314_RS01175	249632..250705	+	1074	WP_040107715.1	hypothetical protein	-
BI314_RS01180	250871..251782	-	912	WP_011050074.1	LysR family transcriptional regulator	-
BI314_RS01185	251908..252645	+	738	WP_003487890.1	SDR family oxidoreductase	-
BI314_RS01190	252705..253604	+	900	WP_011050073.1	SDR family NAD(P)-dependent oxidoreductase	-
BI314_RS01200	253784..254083	-	300	WP_003487886.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BI314_RS01205	254071..254328	-	258	WP_003487884.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BI314_RS01210	254396..255058	-	663	WP_005912558.1	hemolysin III family protein	-
BI314_RS01215	255236..257731	+	2496	WP_015462699.1	DEAD/DEAH box helicase	-
BI314_RS01220	257728..259209	+	1482	WP_015462698.1	ribonuclease H-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11231.97 Da
• Isoelectric Point: 9.7235

>T70696 WP_003487886.1 NZ_CP018847:c254083-253784 [Xanthomonas citri pv. citri]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFGHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T70696 NZ_CP018847:c254083-253784 [Xanthomonas citri pv. citri]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGGGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9683.21 Da
• Isoelectric Point: 9.8274

>AT70696 WP_003487884.1 NZ_CP018847:c254328-254071 [Xanthomonas citri pv. citri]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARHRM
ARWLK

Nucleotide

• Length: 258 bp

>AT70696 NZ_CP018847:c254328-254071 [Xanthomonas citri pv. citri]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCACCGCATG
GCGCGATGGCTGAAATAA

Structures

Toxin

• AlphaFold DB: H8FI26

Antitoxin

• AlphaFold DB: H8FI25