70694

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4836868..4837457 Replicon chromosome
Accession NZ_CP018846
Organism Pseudomonas putida strain AA7

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BUQ73_RS21995 Protein ID WP_079229659.1
Coordinates 4837161..4837457 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag BUQ73_RS21990 Protein ID WP_079229658.1
Coordinates 4836868..4837164 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BUQ73_RS21960 4832571..4832906 - 336 WP_027920288.1 preprotein translocase subunit YajC -
BUQ73_RS21965 4832949..4834064 - 1116 WP_162144435.1 tRNA guanosine(34) transglycosylase Tgt -
BUQ73_RS21970 4834079..4835128 - 1050 WP_079229656.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
BUQ73_RS21980 4835659..4836306 + 648 WP_027920290.1 trypsin-like peptidase domain-containing protein -
BUQ73_RS21985 4836385..4836864 + 480 WP_079229657.1 GNAT family N-acetyltransferase -
BUQ73_RS21990 4836868..4837164 - 297 WP_079229658.1 putative addiction module antidote protein Antitoxin
BUQ73_RS21995 4837161..4837457 - 297 WP_079229659.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BUQ73_RS22000 4837683..4838573 + 891 WP_079229660.1 effector protein -
BUQ73_RS22005 4838604..4839371 - 768 WP_079229661.1 phosphonate ABC transporter, permease protein PhnE -
BUQ73_RS22010 4839368..4840195 - 828 WP_079229662.1 ABC transporter permease -
BUQ73_RS22015 4840189..4840986 - 798 WP_079229663.1 ATP-binding cassette domain-containing protein -
BUQ73_RS22020 4840983..4841837 - 855 WP_079229664.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-86)

Antitoxin

Uncharacterized protein HI1420

(6-92)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10942.83 Da        Isoelectric Point: 10.3193

>T70694 WP_079229659.1 NZ_CP018846:c4837457-4837161 [Pseudomonas putida]
MIYVVEQTKSFGLWLSALKDERAKFAIARRIERAFTGNLGDCKSLGDGLCELRINVSAGYRVYFIYRGKRVLLLLAGGDK
SSQSADILKAKQLAKELK

Download         Length: 297 bp

>T70694 NZ_CP018846:c4837457-4837161 [Pseudomonas putida]
ATGATCTATGTTGTCGAACAAACGAAGAGTTTTGGCTTGTGGTTGTCAGCCTTGAAAGATGAGCGTGCCAAATTCGCGAT
TGCCCGTAGGATCGAGCGAGCGTTTACGGGCAATCTTGGGGATTGCAAGTCACTTGGTGACGGCTTGTGTGAGCTTCGCA
TCAACGTATCTGCGGGCTACCGCGTCTACTTTATCTACCGAGGAAAGCGGGTGTTGCTGTTGCTCGCAGGGGGAGACAAA
TCCTCACAGAGCGCCGACATCCTAAAGGCCAAGCAACTAGCTAAGGAGCTGAAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10551.18 Da        Isoelectric Point: 5.6785

>AT70694 WP_079229658.1 NZ_CP018846:c4837164-4836868 [Pseudomonas putida]
MKEEIIPFDMAALLDSDEAVSEYLSQVLADGDTAEIIRALGHIARAKGMTQIAAQSGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLFAQPHVVSR

Download         Length: 297 bp

>AT70694 NZ_CP018846:c4837164-4836868 [Pseudomonas putida]
ATGAAAGAAGAAATTATTCCTTTCGACATGGCGGCATTGCTCGATAGCGATGAGGCGGTGAGTGAATACCTGAGTCAGGT
GCTGGCTGATGGGGATACCGCTGAAATCATTCGTGCGCTTGGTCATATAGCCCGTGCCAAGGGTATGACTCAGATTGCGG
CGCAAAGCGGGCTGGGTCGAGAGAGCCTCTACAAGGCGCTGAGCCCCGGAGCAAAGCCTCGCTTTGATACCGTGCTGAAG
GTCATACGTGCTCTTGGGGTAGACCTTTTCGCCCAGCCCCACGTTGTTTCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References