70650

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 548277..549629 Replicon chromosome
Accession NZ_CP018836
Organism Vibrio gazogenes strain ATCC 43942

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag BSQ33_RS18095 Protein ID WP_088134841.1
Coordinates 548277..549221 (-) Length 315 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag BSQ33_RS18100 Protein ID WP_088134842.1
Coordinates 549225..549629 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSQ33_RS18075 544528..545847 + 1320 WP_021019942.1 xylose isomerase -
BSQ33_RS18080 545992..546966 - 975 WP_088134839.1 zinc transporter ZntB -
BSQ33_RS18085 547063..547563 - 501 WP_157721430.1 hypothetical protein -
BSQ33_RS18090 547796..548119 - 324 WP_021019945.1 DUF2834 domain-containing protein -
BSQ33_RS18095 548277..549221 - 945 WP_088134841.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
BSQ33_RS18100 549225..549629 - 405 WP_088134842.1 S-adenosylhomocysteine hydrolase Antitoxin
BSQ33_RS18105 549949..550599 + 651 WP_088135295.1 hypothetical protein -
BSQ33_RS18110 550592..551347 + 756 WP_021019949.1 DUF3307 domain-containing protein -
BSQ33_RS18115 551453..552694 - 1242 WP_088134843.1 allantoate amidohydrolase -
BSQ33_RS18120 552756..553988 - 1233 WP_021019951.1 alanine--glyoxylate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-301)

Antitoxin

Protein of unknown function DUF6088

(6-129)


Sequences

Toxin        


Download         Length: 315 a.a.        Molecular weight: 36672.31 Da        Isoelectric Point: 5.8961

>T70650 WP_088134841.1 NZ_CP018836:c549221-548277 [Vibrio gazogenes]
MKKLKEQFLEVSDALALGNPAIIEKDYWVVALLAALEHLTFETHQMVFSGGTALAKSNVKILRMSEDVDIKLIPTDEFNL
LGRDKRKAKRKELVQQLEDALTHQASHFSIEYRNVRDEYRYVEFELKYPQQFSQAPCLRPIIKLELMETIPLLQVEQRGI
QSLVAELYKQPQEVNDFACISVLSTLVEKIISMLRRTMLVKRYPDRKDDATLVRHIYDVYCIEFNQKFDFDALKSLFQTV
LVEDVKRFGNQHAEFVAEPIQELRLGIQELETNPLFRERFTDFVTPMVFNTDTPDFDTCFASFKRIAQSLMNHH

Download         Length: 945 bp

>T70650 NZ_CP018836:c549221-548277 [Vibrio gazogenes]
ATGAAAAAACTAAAAGAGCAATTTTTAGAGGTTTCCGATGCTTTAGCGCTCGGAAATCCTGCCATCATCGAAAAAGATTA
TTGGGTAGTGGCTTTACTTGCTGCGTTAGAACATCTCACTTTTGAAACGCATCAAATGGTGTTTTCCGGTGGAACTGCCT
TAGCTAAATCCAACGTCAAAATCCTCAGAATGTCGGAAGATGTCGACATTAAATTGATCCCAACAGATGAGTTTAATTTA
TTAGGGCGTGATAAGAGAAAAGCCAAACGCAAAGAGCTTGTACAACAACTCGAAGACGCGTTAACTCATCAAGCCAGCCA
TTTTTCTATTGAGTATAGAAATGTTCGTGATGAATATCGCTATGTTGAATTTGAGCTCAAATACCCACAACAATTTAGTC
AAGCACCTTGCTTACGTCCAATTATAAAGTTGGAATTGATGGAAACGATTCCTTTGCTTCAAGTTGAGCAGCGTGGCATT
CAATCACTCGTTGCAGAACTGTATAAACAACCTCAAGAAGTAAACGATTTCGCTTGTATCTCCGTTCTGTCTACATTGGT
CGAAAAAATCATTTCGATGTTGCGCCGTACTATGTTGGTCAAGCGATACCCCGATCGAAAAGATGATGCTACGCTCGTTC
GTCATATCTACGATGTTTACTGCATTGAATTCAACCAAAAATTCGACTTTGATGCCCTTAAGTCTCTTTTTCAAACCGTA
TTAGTAGAAGATGTGAAACGGTTTGGCAATCAACATGCAGAGTTTGTCGCTGAGCCTATTCAAGAATTACGGCTAGGGAT
ACAAGAGTTAGAAACTAACCCATTGTTTCGTGAACGATTTACAGACTTTGTAACGCCAATGGTATTTAATACCGATACAC
CAGACTTCGATACTTGCTTTGCCTCGTTTAAACGCATCGCCCAGTCACTCATGAATCATCATTAG

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15222.51 Da        Isoelectric Point: 10.8115

>AT70650 WP_088134842.1 NZ_CP018836:c549629-549225 [Vibrio gazogenes]
MTAADRINQKLKRSRRYVFERKDFEDIASYDQIGRALNQLIKQGELMKIGYGLYTKARINRLTGRLMPTNPGGSDAILRE
ILKMKGVDFEVDSLSQQSLAGKSTQIPSSVQYSWNPKQFNRKLVVGNRVLNSPS

Download         Length: 405 bp

>AT70650 NZ_CP018836:c549629-549225 [Vibrio gazogenes]
ATGACGGCAGCAGATCGAATCAATCAAAAGTTGAAGCGTTCAAGACGGTATGTTTTTGAGCGCAAAGATTTTGAAGATAT
TGCCAGTTATGACCAGATCGGGCGTGCTCTTAATCAATTGATTAAACAAGGTGAGCTGATGAAAATCGGCTATGGCCTTT
ATACTAAGGCACGTATAAACAGGCTCACGGGCCGTTTAATGCCAACGAACCCAGGCGGCTCCGATGCGATTTTACGTGAA
ATACTAAAGATGAAAGGTGTCGACTTTGAAGTCGATAGCCTATCACAACAAAGTCTTGCAGGTAAAAGCACTCAGATACC
CTCTTCAGTGCAATATTCTTGGAATCCTAAGCAGTTTAATCGCAAGCTGGTTGTTGGTAATCGCGTTCTAAACTCGCCCA
GTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References