Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2740336..2740481 Replicon chromosome
Accession NZ_CP018816
Organism Klebsiella pneumoniae strain AR_0049

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2740372..2740474 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2740336..2740481 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM428_RS14275 2735466..2737526 + 2061 WP_004151449.1 oligopeptidase B -
AM428_RS14285 2737530..2738189 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM428_RS14290 2738268..2738498 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM428_RS14295 2738611..2738985 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM428_RS14300 2738989..2739858 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AM428_RS14305 2739875..2740213 + 339 WP_004189269.1 YebY family protein -
- 2740336..2740481 - 146 - - Antitoxin
- 2740372..2740474 + 103 - - Toxin
AM428_RS32445 2740848..2740991 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM428_RS14320 2741096..2742064 - 969 WP_004151446.1 VirK/YbjX family protein -
AM428_RS14325 2742221..2742874 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
AM428_RS14330 2742871..2743062 - 192 WP_002911395.1 YebW family protein -
AM428_RS14335 2743160..2743399 - 240 WP_002911393.1 YebV family protein -
AM428_RS14340 2743515..2744948 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T70616 NZ_CP018816:2740372-2740474 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT70616 NZ_CP018816:c2740481-2740336 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References