Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1271535..1273036 Replicon chromosome
Accession NZ_CP018799
Organism Mariprofundus aestuarium strain CP-5

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag Ga0123461_RS06210 Protein ID WP_100277542.1
Coordinates 1272152..1273036 (+) Length 295 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag Ga0123461_RS06205 Protein ID WP_100277541.1
Coordinates 1271535..1272155 (+) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ga0123461_RS06195 1267930..1270263 - 2334 WP_100277539.1 hypothetical protein -
Ga0123461_RS06200 1270250..1271023 - 774 WP_100277540.1 hypothetical protein -
Ga0123461_RS06205 1271535..1272155 + 621 WP_100277541.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
Ga0123461_RS06210 1272152..1273036 + 885 WP_100277542.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
Ga0123461_RS06215 1273534..1275087 + 1554 WP_157819258.1 undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase -
Ga0123461_RS06220 1275194..1276744 + 1551 WP_100277544.1 hypothetical protein -
Ga0123461_RS06225 1276800..1277414 - 615 WP_100277545.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - gmd / fcl 1247020..1280415 33395


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-263)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-57)


Sequences

Toxin        


Download         Length: 295 a.a.        Molecular weight: 32971.84 Da        Isoelectric Point: 5.9365

>T70533 WP_100277542.1 NZ_CP018799:1272152-1273036 [Mariprofundus aestuarium]
MTGKGVNTAASIRQRLLNIAREQKVDFNRILTDYGLQRLLFRLSASKYRDEFVLKGAMLFSYWSGDVYRATKDIDFLKSG
DASIAYLKQVFIDLSYQDVVPDDGLIFDPASVKAEEIREEDSYGGIRVTLKATLSGARVSMQADIGIGDVITPAAQDIEY
PVLLDLPSPKLKAYPVETVIAEKFEAMVYLGFANSRMKDFYDIWALLRFMKPDHDLIAKAIANTFRRRGTALPSDVPVAL
TSEFSRDDMKQKQWAAFVRRAAVGSSAKATLHETVEEIRPLLLGLVDIVRNNDE

Download         Length: 885 bp

>T70533 NZ_CP018799:1272152-1273036 [Mariprofundus aestuarium]
ATGACTGGCAAAGGTGTAAATACAGCGGCATCTATTCGCCAGCGTCTGCTGAATATTGCACGCGAACAGAAGGTCGATTT
TAATCGCATCCTGACCGACTATGGATTGCAGCGATTACTTTTCCGGTTGTCGGCTTCGAAGTATCGAGATGAGTTCGTCC
TAAAGGGTGCGATGCTTTTCTCTTACTGGAGCGGTGATGTTTACCGAGCCACCAAGGATATCGATTTCCTGAAATCCGGA
GATGCCTCGATTGCTTATCTTAAGCAGGTGTTTATAGACCTAAGTTATCAAGATGTCGTGCCTGATGATGGGTTGATTTT
TGATCCAGCATCGGTAAAGGCTGAGGAGATCAGAGAAGAAGATTCCTACGGAGGTATTCGGGTCACCTTGAAAGCAACGC
TTTCTGGTGCTCGTGTCTCGATGCAGGCAGATATTGGTATCGGTGATGTAATTACTCCGGCGGCACAGGACATCGAGTAT
CCAGTCCTGTTGGATTTACCGTCACCTAAACTCAAAGCTTACCCTGTAGAAACAGTCATCGCAGAAAAATTCGAGGCCAT
GGTTTATCTCGGATTTGCCAATAGCCGGATGAAAGATTTCTATGACATCTGGGCCTTGTTGAGATTTATGAAGCCGGATC
ACGACCTGATTGCCAAGGCGATTGCCAACACATTCAGACGGCGTGGAACTGCGCTTCCTTCGGATGTACCAGTGGCTTTG
ACCAGTGAGTTTTCAAGGGATGATATGAAGCAGAAGCAGTGGGCTGCATTTGTCAGGCGAGCCGCAGTTGGGAGCAGTGC
AAAAGCGACTCTGCATGAAACAGTTGAAGAGATCAGGCCGCTGTTGTTGGGTCTGGTAGATATTGTGAGGAATAATGATG
AATGA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 23588.48 Da        Isoelectric Point: 9.8834

>AT70533 WP_100277541.1 NZ_CP018799:1271535-1272155 [Mariprofundus aestuarium]
MRHSYNNQTATERILSLLKERGVIRPRDLDEYNIPRRYLSRLYERGIILRSSRGIYMAAYAELSEMQTIVEASKRIPKGT
VCLLTALAVHEMTTQAPFEVWLAIDRKDWLPQISDLPVRIVRFSGDALKSGIEHRVIDGVTVPVYNPAKTVVDCFKYRNK
IGLDVAIEALKGGWRAKKFSMDDIRKYAGVCRVQNVMQPYLETLIG

Download         Length: 621 bp

>AT70533 NZ_CP018799:1271535-1272155 [Mariprofundus aestuarium]
ATGAGACATTCATATAATAATCAGACAGCTACAGAACGAATTCTATCGCTTCTAAAAGAACGCGGTGTTATTCGCCCTCG
TGACCTTGATGAGTATAATATTCCACGTCGATATCTGAGTCGCCTTTACGAGCGGGGAATCATCCTTCGCTCTTCTCGTG
GCATATACATGGCGGCCTATGCCGAGCTTTCAGAGATGCAGACTATCGTAGAGGCCAGCAAGCGAATCCCCAAGGGAACG
GTATGCCTGCTTACTGCACTGGCGGTTCATGAGATGACCACGCAGGCACCCTTTGAAGTCTGGCTGGCGATTGATCGAAA
AGATTGGCTACCACAGATAAGCGACCTGCCTGTCCGAATCGTCCGTTTTTCTGGCGATGCCCTGAAGAGCGGCATTGAAC
ATCGAGTGATCGATGGCGTTACCGTGCCTGTCTATAACCCAGCCAAGACGGTTGTCGACTGCTTTAAATACAGAAACAAG
ATTGGACTGGATGTGGCAATTGAAGCCCTGAAAGGTGGTTGGAGGGCCAAGAAGTTTTCTATGGATGACATCCGGAAGTA
TGCTGGTGTTTGCAGGGTTCAGAATGTCATGCAGCCATACCTTGAGACTCTCATAGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References