Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1209102..1209609 Replicon chromosome
Accession NZ_CP018799
Organism Mariprofundus aestuarium strain CP-5

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag Ga0123461_RS05960 Protein ID WP_100277496.1
Coordinates 1209349..1209609 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Ga0123461_RS05955 Protein ID WP_100277495.1
Coordinates 1209102..1209356 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ga0123461_RS05930 1204210..1205190 - 981 WP_100277490.1 NAD(P)-dependent alcohol dehydrogenase -
Ga0123461_RS05935 1205187..1206170 - 984 WP_100277491.1 NAD(P)-dependent alcohol dehydrogenase -
Ga0123461_RS05940 1206663..1207835 + 1173 WP_100277492.1 N(5)-(carboxyethyl)ornithine synthase -
Ga0123461_RS05945 1207847..1208482 + 636 WP_100277493.1 MarC family protein -
Ga0123461_RS05950 1208703..1208948 + 246 WP_100277494.1 RNA-binding protein -
Ga0123461_RS05955 1209102..1209356 + 255 WP_100277495.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Ga0123461_RS05960 1209349..1209609 + 261 WP_100277496.1 Txe/YoeB family addiction module toxin Toxin
Ga0123461_RS05965 1209690..1210181 + 492 WP_100277497.1 asparaginase -
Ga0123461_RS05970 1210371..1210820 + 450 WP_198507162.1 VF530 family protein -
Ga0123461_RS05975 1210874..1213468 + 2595 WP_100277499.1 ATP-dependent helicase HrpB -
Ga0123461_RS05980 1213562..1214482 - 921 WP_100277500.1 phosphatidylserine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10424.80 Da        Isoelectric Point: 6.9490

>T70532 WP_100277496.1 NZ_CP018799:1209349-1209609 [Mariprofundus aestuarium]
MPELLCWTDEAWADYLWWQSQDRKTLKRINRLIQDSMRSPFEGIGKPEALRENLSGFWSRRIDESNRLVYAVDDNRLTII
SCRYHY

Download         Length: 261 bp

>T70532 NZ_CP018799:1209349-1209609 [Mariprofundus aestuarium]
ATGCCTGAATTACTATGCTGGACAGATGAGGCATGGGCTGACTATCTCTGGTGGCAGAGTCAGGATCGCAAAACCCTGAA
GCGAATCAACCGCCTGATTCAGGATTCAATGCGCTCTCCTTTTGAAGGTATTGGAAAGCCGGAAGCACTGCGTGAAAACC
TCTCTGGTTTCTGGTCTCGTCGGATTGATGAATCTAATCGCCTGGTTTATGCCGTTGATGATAACCGATTAACCATCATC
TCCTGCCGCTACCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9409.54 Da        Isoelectric Point: 4.7483

>AT70532 WP_100277495.1 NZ_CP018799:1209102-1209356 [Mariprofundus aestuarium]
MQVVNFSEARNNLKRVLDEVVEDADYTVINRRDAADTVVMSLDSFNSLMETVHLLRSSANVAHLEKSISQYNQGKASEKP
LIDA

Download         Length: 255 bp

>AT70532 NZ_CP018799:1209102-1209356 [Mariprofundus aestuarium]
ATGCAAGTTGTCAATTTTTCAGAAGCCAGAAACAATCTGAAACGCGTATTGGATGAGGTTGTTGAGGATGCCGATTACAC
AGTTATTAATCGACGAGATGCAGCCGATACGGTTGTGATGTCTCTGGATTCATTCAACAGTTTGATGGAAACAGTTCACC
TGCTACGTTCTTCTGCCAATGTTGCCCATCTGGAAAAATCAATCTCCCAGTATAATCAGGGGAAAGCTTCTGAAAAGCCG
TTGATTGATGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References