Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 20241..21129 Replicon plasmid pVIC12175-1
Accession NZ_CP018794
Organism Campylobacter sp. RM12175

Toxin (Protein)


Gene name Fic Uniprot ID -
Locus tag CVIC12175_RS08390 Protein ID WP_086257348.1
Coordinates 20473..21129 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name Fti Uniprot ID -
Locus tag CVIC12175_RS08385 Protein ID WP_086257349.1
Coordinates 20241..20489 (+) Length 83 a.a.

Genomic Context

CVIC12175_RS08370CVIC12175_RS08375CVIC12175_RS08380CVIC12175_RS08385CVIC12175_RS08390CVIC12175_RS08395CVIC12175_RS08400CVIC12175_RS08405CVIC12175_RS08410CVIC12175_RS08415CVIC12175_RS08420
Location: 15380..17569 (2190 bp)
Type: Others
Protein ID: WP_086257351.1
Location: 17579..19405 (1827 bp)
Type: Others
Protein ID: WP_086257350.1
Location: 19417..20124 (708 bp)
Type: Others
Protein ID: WP_002850984.1
Location: 20241..20489 (249 bp)
Type: Antitoxin
Protein ID: WP_086257349.1
Location: 20473..21129 (657 bp)
Type: Toxin
Protein ID: WP_086257348.1
Location: 21190..21648 (459 bp)
Type: Others
Protein ID: WP_086257347.1
Location: 21645..22016 (372 bp)
Type: Others
Protein ID: WP_086257346.1
Location: 22127..22813 (687 bp)
Type: Others
Protein ID: WP_086257345.1
Location: 22817..23026 (210 bp)
Type: Others
Protein ID: WP_040126369.1
Location: 23101..24663 (1563 bp)
Type: Others
Protein ID: WP_086257344.1
Location: 24638..25006 (369 bp)
Type: Others
Protein ID: WP_086257343.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CVIC12175_RS0837015380..17569+2190WP_086257351.1DUF1738 domain-containing protein-
CVIC12175_RS0837517579..19405+1827WP_086257350.1type IV secretory system conjugative DNA transfer family protein-
CVIC12175_RS0838019417..20124+708WP_002850984.1conjugal transfer protein TraL-
CVIC12175_RS0838520241..20489+249WP_086257349.1hypothetical proteinAntitoxin
CVIC12175_RS0839020473..21129+657WP_086257348.1Fic family proteinToxin
CVIC12175_RS0839521190..21648+459WP_086257347.1S26 family signal peptidase-
CVIC12175_RS0840021645..22016+372WP_086257346.1conjugal transfer protein TraM-
CVIC12175_RS0840522127..22813+687WP_086257345.1AAA family ATPase-
CVIC12175_RS0841022817..23026+210WP_040126369.1hypothetical protein-
CVIC12175_RS0841523101..24663-1563WP_086257344.1relaxase/mobilization nuclease domain-containing protein-
CVIC12175_RS0842024638..25006-369WP_086257343.1DNA transfer protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..2522025220


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(50-159)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25217.90 Da        Isoelectric Point: 9.9201

>T70530 WP_086257348.1 NZ_CP018794:20473-21129 [Campylobacter sp. RM12175]
MKENNEELFKRLITDNKLGIKDEKLFDKESRFYTGLRERELTLNPIKGNFDYQHLKNIHKHIFQDVFHWAGKDRMEVGLH
GNFGKYAPNGTITNFVPGKDLNATAQQIFTWLKEDNYLKNSKDLNDFAKNLAEFARNLNSLHPFREGNGRTQRIFLNELA
KNAGYKLDLNLIPKDKMIMASVEASQLKLGKLEALIKTNLKSFKQNLEKENTLGLSLC

Download         Length: 657 bp

>T70530 NZ_CP018794:20473-21129 [Campylobacter sp. RM12175]
ATGAAAGAAAACAATGAAGAACTTTTTAAAAGATTAATTACAGATAATAAACTCGGTATAAAAGATGAAAAATTATTTGA
TAAAGAATCAAGATTTTATACTGGTTTAAGAGAAAGAGAGCTTACGCTCAATCCTATCAAAGGCAATTTCGATTATCAGC
ACTTAAAAAATATACATAAACATATTTTTCAAGATGTATTTCACTGGGCTGGAAAAGATAGAATGGAAGTAGGCTTGCAT
GGAAATTTTGGAAAATATGCACCAAATGGAACAATTACTAATTTTGTTCCTGGAAAAGATTTAAATGCAACCGCTCAACA
AATTTTTACTTGGCTTAAAGAAGACAATTACTTAAAAAATTCAAAAGATCTTAACGATTTTGCAAAGAACTTAGCCGAAT
TTGCTAGAAACCTAAATTCTTTGCACCCCTTTAGAGAAGGTAACGGCAGAACTCAAAGAATATTTTTAAATGAATTGGCT
AAAAATGCAGGTTATAAACTTGATTTAAATTTAATACCAAAAGATAAAATGATAATGGCATCTGTAGAAGCTTCACAATT
GAAATTAGGAAAACTAGAAGCCTTAATAAAAACAAATCTAAAAAGCTTTAAGCAAAATTTAGAAAAAGAAAATACATTAG
GCTTATCCCTATGTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9528.86 Da        Isoelectric Point: 4.5686

>AT70530 WP_086257349.1 NZ_CP018794:20241-20489 [Campylobacter sp. RM12175]
MTYPEVHSLEESLAILKKYKDDVNKEDYEGIKSVISNHAIESIYMNELDIIAMIKQSALKLSADEIIAEYKEKGFVEYER
KQ

Download         Length: 249 bp

>AT70530 NZ_CP018794:20241-20489 [Campylobacter sp. RM12175]
ATGACATATCCAGAAGTGCATAGTTTAGAAGAAAGTTTAGCAATACTTAAAAAATATAAAGATGATGTAAATAAGGAAGA
TTATGAAGGTATAAAATCTGTTATAAGTAATCATGCGATAGAGAGTATTTACATGAATGAATTAGATATTATCGCTATGA
TAAAACAAAGTGCTTTAAAGTTAAGTGCTGATGAAATCATTGCTGAATATAAGGAAAAGGGATTTGTAGAATATGAAAGA
AAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References