Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3831346..3831934 Replicon chromosome
Accession NZ_CP018760
Organism Maribacter sp. T28

Toxin (Protein)


Gene name PumA Uniprot ID A0A1B7Z5R3
Locus tag BTR34_RS16405 Protein ID WP_068485159.1
Coordinates 3831632..3831934 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1B7Z5R8
Locus tag BTR34_RS16400 Protein ID WP_068485161.1
Coordinates 3831346..3831630 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTR34_RS16385 3827373..3827669 - 297 WP_068483162.1 hypothetical protein -
BTR34_RS16390 3828117..3829850 - 1734 WP_068483165.1 CocE/NonD family hydrolase -
BTR34_RS16395 3830246..3831214 + 969 WP_074472153.1 transposase -
BTR34_RS16400 3831346..3831630 - 285 WP_068485161.1 putative addiction module antidote protein Antitoxin
BTR34_RS16405 3831632..3831934 - 303 WP_068485159.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BTR34_RS16410 3832167..3833153 - 987 WP_157483873.1 hypothetical protein -
BTR34_RS16415 3833571..3834539 + 969 WP_074472153.1 transposase -
BTR34_RS16420 3834669..3835199 - 531 WP_068485164.1 hypothetical protein -
BTR34_RS16425 3835212..3835598 - 387 WP_082960185.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-93)

Antitoxin

Uncharacterized protein HI1420

(2-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11834.81 Da        Isoelectric Point: 10.2800

>T70394 WP_068485159.1 NZ_CP018760:c3831934-3831632 [Maribacter sp. T28]
MIITEKTTEFDKWIRKLKDIRAKSKILFRIQKLETDEHFGDCKPVGDGISEMRINYAKGYRVYFKEKDNKIVILLIGGDK
SSQQKDIDKAKKIWNRIKND

Download         Length: 303 bp

>T70394 NZ_CP018760:c3831934-3831632 [Maribacter sp. T28]
ATGATTATCACCGAAAAAACAACTGAATTTGATAAGTGGATTAGAAAGCTCAAAGATATTCGAGCGAAATCTAAAATACT
CTTCCGAATTCAGAAACTCGAAACCGATGAGCATTTTGGAGATTGTAAGCCTGTTGGAGATGGAATTAGCGAAATGCGGA
TTAATTATGCCAAAGGTTATCGAGTGTATTTTAAGGAAAAAGATAACAAGATTGTCATCCTTTTAATCGGTGGAGATAAA
TCAAGCCAACAAAAGGATATTGACAAAGCGAAGAAAATTTGGAACAGAATAAAAAATGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10000.60 Da        Isoelectric Point: 4.7085

>AT70394 WP_068485161.1 NZ_CP018760:c3831630-3831346 [Maribacter sp. T28]
MATTKFDIADYLDSEEMIAEYLNTVLEDGDSSDLIVAIGNIAKAIGMTKIAEKSGMSRPSLYKALSDGAKPQFGTIMKVL
KAIGGQINVKPMSA

Download         Length: 285 bp

>AT70394 NZ_CP018760:c3831630-3831346 [Maribacter sp. T28]
ATGGCAACAACAAAATTTGATATTGCGGACTATTTGGACAGCGAAGAAATGATTGCTGAATATCTTAATACAGTTCTTGA
AGATGGAGATAGTTCTGATTTAATTGTGGCAATCGGAAATATTGCAAAGGCAATCGGAATGACTAAAATTGCGGAGAAAT
CTGGAATGAGCCGACCAAGTCTTTACAAAGCTTTATCTGATGGAGCAAAACCGCAATTCGGAACGATAATGAAAGTATTG
AAAGCAATTGGCGGACAAATTAATGTGAAACCAATGTCAGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B7Z5R3

Antitoxin

Source ID Structure
AlphaFold DB A0A1B7Z5R8

References