Detailed information of TA system TA070393

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PfiT-PfiA/-
• Location: 3045351..3045931
• Replicon: chromosome
• Accession: NZ_CP018758
• Organism: Pseudomonas psychrotolerans strain PRS08-11306

Toxin (Protein)

• Gene name: PfiT
• Uniprot ID: -
• Locus tag: BJP27_RS13735
• Protein ID: WP_058772043.1
• Coordinates: 3045351..3045686 (-)
• Length: 112 a.a.

Antitoxin (Protein)

• Gene name: PfiA
• Uniprot ID: A0A147HAQ7
• Locus tag: BJP27_RS13740
• Protein ID: WP_058761773.1
• Coordinates: 3045683..3045931 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJP27_RS13705	3040555..3040809	+	255	WP_058761766.1	hypothetical protein	-
BJP27_RS13710	3040845..3041714	-	870	WP_208613084.1	alpha/beta fold hydrolase	-
BJP27_RS13715	3041725..3042810	-	1086	WP_074528971.1	tartrate dehydrogenase	-
BJP27_RS13720	3042914..3043810	+	897	WP_074528972.1	LysR family transcriptional regulator	-
BJP27_RS13725	3043884..3044723	+	840	WP_058772044.1	AraC family transcriptional regulator	-
BJP27_RS13730	3044770..3045354	+	585	WP_058767060.1	LysE family translocator	-
BJP27_RS13735	3045351..3045686	-	336	WP_058772043.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BJP27_RS13740	3045683..3045931	-	249	WP_058761773.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BJP27_RS13745	3046060..3046968	-	909	WP_058761774.1	LysR family transcriptional regulator	-
BJP27_RS13750	3047079..3047681	+	603	WP_074528973.1	FMN-dependent NADH-azoreductase	-
BJP27_RS13755	3048192..3049172	-	981	WP_074528974.1	aldo/keto reductase	-
BJP27_RS13760	3049290..3049718	+	429	WP_058761777.1	OsmC family protein	-
BJP27_RS13765	3050184..3050417	-	234	WP_074528975.1	hypothetical protein	-
BJP27_RS13770	3050481..3050897	-	417	WP_058767057.1	MarR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-99)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 112 a.a.
• Molecular weight: 12458.48 Da
• Isoelectric Point: 7.1157

>T70393 WP_058772043.1 NZ_CP018758:c3045686-3045351 [Pseudomonas psychrotolerans]
MSVTLRFTECAALSLEDQIHHLADHIGQQAALTKITGLINAIESQLPAAPLAFPVSHQASELGLLHYREFNHYGFRVFYE
IKAAEEAVVVLLVLRQKQSVEKALIRHCLLR

Nucleotide

• Length: 336 bp

>T70393 NZ_CP018758:c3045686-3045351 [Pseudomonas psychrotolerans]
ATGAGCGTCACGCTGCGTTTCACCGAGTGCGCCGCCCTGAGCCTGGAAGATCAGATCCATCACCTGGCCGATCACATTGG
CCAGCAGGCCGCGCTCACTAAAATCACTGGATTGATCAACGCCATCGAAAGCCAGCTACCTGCAGCGCCTCTGGCCTTTC
CTGTAAGCCACCAAGCCAGTGAGCTCGGCCTACTGCACTATCGCGAATTCAACCACTACGGTTTTCGGGTCTTCTACGAG
ATCAAGGCCGCCGAAGAAGCCGTGGTCGTGCTGCTGGTGCTCAGGCAGAAGCAGAGCGTCGAAAAGGCGCTGATTCGCCA
CTGTCTACTGCGCTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9472.68 Da
• Isoelectric Point: 7.2029

>AT70393 WP_058761773.1 NZ_CP018758:c3045931-3045683 [Pseudomonas psychrotolerans]
MKTETISYLKRHAANLDLDEPMIVTQNGVPAYVIESYQERRRRDEAVALVKLLALSSREDAEGRHQTADQLKDRLARRFS
TE

Nucleotide

• Length: 249 bp

>AT70393 NZ_CP018758:c3045931-3045683 [Pseudomonas psychrotolerans]
ATGAAGACCGAGACCATCAGCTATCTGAAACGCCATGCGGCCAATCTTGATTTGGACGAGCCCATGATCGTGACCCAGAA
CGGTGTGCCGGCCTATGTCATCGAGTCCTACCAGGAGCGCCGCCGCCGCGACGAGGCGGTGGCCCTGGTCAAGCTGCTGG
CCTTGAGTTCGCGGGAAGACGCAGAGGGTCGACACCAGACGGCTGACCAATTGAAAGATCGCCTGGCCCGGCGTTTCTCC
ACGGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A147HAQ7