Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1413418..1413923 Replicon chromosome
Accession NZ_CP018731
Organism Xanthomonas hortorum pv. gardneri strain ICMP 7383

Toxin (Protein)


Gene name relE Uniprot ID A0A6V7D3A5
Locus tag BI317_RS06605 Protein ID WP_074056859.1
Coordinates 1413418..1413675 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag BI317_RS06610 Protein ID WP_006448404.1
Coordinates 1413672..1413923 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI317_RS06580 1409117..1410472 + 1356 WP_074056857.1 aminodeoxychorismate synthase component I -
BI317_RS06585 1410488..1411597 + 1110 WP_074056858.1 endolytic transglycosylase MltG -
BI317_RS06590 1411594..1412553 + 960 WP_006448409.1 DNA polymerase III subunit delta' -
BI317_RS06595 1412550..1412903 + 354 WP_003483889.1 PilZ domain-containing protein -
BI317_RS06605 1413418..1413675 - 258 WP_074056859.1 Txe/YoeB family addiction module toxin Toxin
BI317_RS06610 1413672..1413923 - 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BI317_RS06615 1414109..1414435 + 327 WP_074056860.1 hypothetical protein -
BI317_RS06620 1414678..1416297 - 1620 WP_174555969.1 propionate catabolism operon regulatory protein PrpR -
BI317_RS06625 1416426..1417322 + 897 WP_074056861.1 methylisocitrate lyase -
BI317_RS06630 1417398..1418552 + 1155 WP_074056862.1 2-methylcitrate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.66 Da        Isoelectric Point: 9.6587

>T70368 WP_074056859.1 NZ_CP018731:c1413675-1413418 [Xanthomonas hortorum pv. gardneri]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYG

Download         Length: 258 bp

>T70368 NZ_CP018731:c1413675-1413418 [Xanthomonas hortorum pv. gardneri]
GTGATTCTGCAGTTTGCTGACAATGCCTGGGAGGACTACCTCTACTGGCAACAGACCGACAAGAAGATGCTCAAACGCAT
CAACGAGTTGATCAAGGCCATTCAGCGCGATCCTTTCCAGGGCATCGGCAAACCCGAACCGTTGCGCCATGCGCTGGCGG
GCTACTGGTCACGCCGCATCAACGACGAACACCGGATCGTTTACAAGGCCGAGAACGGCATCCTGTTGATTGCTCAGGCG
CGCTACCACTACGGGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT70368 WP_006448404.1 NZ_CP018731:c1413923-1413672 [Xanthomonas hortorum pv. gardneri]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp

>AT70368 NZ_CP018731:c1413923-1413672 [Xanthomonas hortorum pv. gardneri]
ATGGACACCATCACCTACAGCGCCGCGCGTGCCTCTCTGGCCGACACCATGGACCGTGTCGTCAATGACCACGAGCCGGT
GATCATCACGCGCAGCGGTGAGCGCGCCGTGGTCATGGTGTCGCTGGAAGATTACAAGGCCATGGAAGAGACCGCCTACC
TGTTGCGCAGCCCGAAGAGTGCGCAACGGCTGCTGGAATCCATTGCCCAGCTTGAGGCCGGTCGCGGCAAGGAACGGGAA
CTGGCTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7D3A5

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References