70367

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 608418..608783 Replicon chromosome
Accession NZ_CP018731
Organism Xanthomonas hortorum pv. gardneri strain ICMP 7383

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6V7C9X4
Locus tag BI317_RS02630 Protein ID WP_074056472.1
Coordinates 608649..608783 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag BI317_RS02625 Protein ID WP_006451340.1
Coordinates 608418..608570 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI317_RS02600 604498..605040 - 543 WP_074056470.1 GTPase -
BI317_RS02605 605037..605954 - 918 WP_074056471.1 hypothetical protein -
BI317_RS02610 606048..606407 - 360 WP_006452081.1 hypothetical protein -
BI317_RS02615 606471..606923 - 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
BI317_RS02620 607385..608308 + 924 WP_074058724.1 arginase -
BI317_RS02625 608418..608570 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
BI317_RS02630 608649..608783 + 135 WP_074056472.1 entericidin A/B family lipoprotein Toxin
BI317_RS02635 609025..609234 + 210 WP_006451342.1 CsbD family protein -
BI317_RS02640 609408..610697 + 1290 WP_074056473.1 tryptophan--tRNA ligase -
BI317_RS02645 610905..611849 + 945 WP_095575004.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.31 Da        Isoelectric Point: 9.3487

>T70367 WP_074056472.1 NZ_CP018731:608649-608783 [Xanthomonas hortorum pv. gardneri]
MKRAIILLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70367 NZ_CP018731:608649-608783 [Xanthomonas hortorum pv. gardneri]
ATGAAGCGTGCAATTATACTGCTGGTGCTGTCGGTGTTTTCGGTCGGTATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAAGTGGAAGACGCTGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT70367 WP_006451340.1 NZ_CP018731:608418-608570 [Xanthomonas hortorum pv. gardneri]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT70367 NZ_CP018731:608418-608570 [Xanthomonas hortorum pv. gardneri]
ATGAAGCGACTGCTGACACTGATGGTGCTAGGCCTGTTTTCGGCTGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGCGCAGGTGAGAAGGTCGAAAAGAAGGCCGATAATTGCAGCGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7C9X4

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References