Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1915309..1915814 Replicon chromosome
Accession NZ_CP018728
Organism Xanthomonas hortorum pv. gardneri strain JS749-3

Toxin (Protein)


Gene name relE Uniprot ID F0BZT0
Locus tag BJD10_RS08735 Protein ID WP_006448405.1
Coordinates 1915309..1915566 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag BJD10_RS08740 Protein ID WP_006448404.1
Coordinates 1915563..1915814 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD10_RS08710 1910991..1912346 + 1356 WP_006448411.1 aminodeoxychorismate synthase component I -
BJD10_RS08715 1912362..1913471 + 1110 WP_043907083.1 endolytic transglycosylase MltG -
BJD10_RS08720 1913468..1914427 + 960 WP_006448409.1 DNA polymerase III subunit delta' -
BJD10_RS08725 1914424..1914777 + 354 WP_003483889.1 PilZ domain-containing protein -
BJD10_RS08735 1915309..1915566 - 258 WP_006448405.1 Txe/YoeB family addiction module toxin Toxin
BJD10_RS08740 1915563..1915814 - 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BJD10_RS08745 1916000..1916326 + 327 WP_006448403.1 hypothetical protein -
BJD10_RS08750 1916569..1918170 - 1602 WP_006448402.1 propionate catabolism operon regulatory protein PrpR -
BJD10_RS08755 1918317..1919213 + 897 WP_006448401.1 methylisocitrate lyase -
BJD10_RS08760 1919289..1920443 + 1155 WP_006448400.1 2-methylcitrate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10200.71 Da        Isoelectric Point: 9.6587

>T70365 WP_006448405.1 NZ_CP018728:c1915566-1915309 [Xanthomonas hortorum pv. gardneri]
VILQFADNTWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYA

Download         Length: 258 bp

>T70365 NZ_CP018728:c1915566-1915309 [Xanthomonas hortorum pv. gardneri]
GTGATTCTGCAGTTTGCTGACAATACCTGGGAGGACTACCTCTACTGGCAACAGACCGACAAGAAGATGCTCAAACGCAT
CAACGAGTTGATCAAGGCCATTCAGCGCGATCCTTTCCAGGGCATCGGCAAACCCGAACCGTTGCGCCATGCGCTGGCGG
GCTACTGGTCACGCCGCATCAACGACGAACACCGGATTGTCTACAAGGCCGAGAACGGCATCCTGCTGATTGCTCAGGCG
CGCTACCACTACGCGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT70365 WP_006448404.1 NZ_CP018728:c1915814-1915563 [Xanthomonas hortorum pv. gardneri]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp

>AT70365 NZ_CP018728:c1915814-1915563 [Xanthomonas hortorum pv. gardneri]
ATGGACACCATCACCTACAGCGCCGCGCGTGCCTCTCTGGCCGACACCATGGACCGTGTCGTCAATGACCACGAGCCGGT
GATCATCACGCGCAGCGGTGAGCGCGCCGTGGTCATGGTGTCGCTGGAAGATTACAAGGCCATGGAAGAGACCGCCTACC
TGTTGCGCAGCCCGAAGAGTGCGCAACGGCTGCTGGAATCCATTGCCCAGCTTGAGGCCGGTCGCGGCAAGGAACGGGAA
CTGGCTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7E8S3

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References