70364

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1027890..1028255 Replicon chromosome
Accession NZ_CP018728
Organism Xanthomonas hortorum pv. gardneri strain JS749-3

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag BJD10_RS04480 Protein ID WP_006451341.1
Coordinates 1028121..1028255 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag BJD10_RS04475 Protein ID WP_006451340.1
Coordinates 1027890..1028042 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD10_RS04450 1023972..1024514 - 543 WP_006452083.1 hypothetical protein -
BJD10_RS04455 1024511..1025428 - 918 WP_043910206.1 hypothetical protein -
BJD10_RS04460 1025520..1025879 - 360 WP_006452081.1 hypothetical protein -
BJD10_RS04465 1025943..1026395 - 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
BJD10_RS04470 1026857..1027780 + 924 WP_046931980.1 arginase -
BJD10_RS04475 1027890..1028042 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
BJD10_RS04480 1028121..1028255 + 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
BJD10_RS04485 1028497..1028706 + 210 WP_006451342.1 CsbD family protein -
BJD10_RS04490 1028880..1030169 + 1290 WP_043909456.1 tryptophan--tRNA ligase -
BJD10_RS04495 1030228..1031172 + 945 WP_006451344.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T70364 WP_006451341.1 NZ_CP018728:1028121-1028255 [Xanthomonas hortorum pv. gardneri]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70364 NZ_CP018728:1028121-1028255 [Xanthomonas hortorum pv. gardneri]
ATGAAGCGTGCAATTATGCTGCTGGTGCTGTCGGTGTTTTCGGTCGGTATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAAGTGGAAGACGCTGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT70364 WP_006451340.1 NZ_CP018728:1027890-1028042 [Xanthomonas hortorum pv. gardneri]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT70364 NZ_CP018728:1027890-1028042 [Xanthomonas hortorum pv. gardneri]
ATGAAGCGACTGCTGACACTGATGGTGCTAGGCCTGTTTTCGGCTGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGCGCAGGTGAGAAGGTCGAAAAGAAGGCCGATAATTGCAGCGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References