Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2450822..2451187 Replicon chromosome
Accession NZ_CP018725
Organism Xanthomonas vesicatoria ATCC 35937 strain LMG911

Toxin (Protein)


Gene name EcnB Uniprot ID F0B9H9
Locus tag BJD12_RS10755 Protein ID WP_005989324.1
Coordinates 2450822..2450956 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1L5QT75
Locus tag BJD12_RS10760 Protein ID WP_039421598.1
Coordinates 2451035..2451187 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD12_RS10740 2447794..2448732 - 939 WP_005989319.1 MBL fold metallo-hydrolase -
BJD12_RS10745 2448931..2450220 - 1290 WP_005989321.1 tryptophan--tRNA ligase -
BJD12_RS10750 2450392..2450601 - 210 WP_005989323.1 CsbD family protein -
BJD12_RS10755 2450822..2450956 - 135 WP_005989324.1 entericidin A/B family lipoprotein Toxin
BJD12_RS10760 2451035..2451187 - 153 WP_039421598.1 entericidin A/B family lipoprotein Antitoxin
BJD12_RS10765 2451297..2452220 - 924 WP_005989327.1 arginase -
BJD12_RS10770 2452540..2452992 + 453 WP_005989338.1 roadblock/LC7 domain-containing protein -
BJD12_RS10775 2453061..2453420 + 360 WP_005989340.1 hypothetical protein -
BJD12_RS10780 2453515..2454432 + 918 WP_042827691.1 hypothetical protein -
BJD12_RS10785 2454429..2454968 + 540 WP_005989344.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4523.37 Da        Isoelectric Point: 9.3487

>T70362 WP_005989324.1 NZ_CP018725:c2450956-2450822 [Xanthomonas vesicatoria ATCC 35937]
MKRAIVLLVLSMFSVAMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70362 NZ_CP018725:c2450956-2450822 [Xanthomonas vesicatoria ATCC 35937]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTCTCGGTCGCGATGTTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGTAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5141.09 Da        Isoelectric Point: 8.2782

>AT70362 WP_039421598.1 NZ_CP018725:c2451187-2451035 [Xanthomonas vesicatoria ATCC 35937]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT70362 NZ_CP018725:c2451187-2451035 [Xanthomonas vesicatoria ATCC 35937]
ATGAAGCGACTGCTGACACTAATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACTGGTTGCAACACCATGGCTGGCGC
CGGCAAGGACATGCAAGGTGCGGGCGACAAGGTCGAAAAGACCGCCGATAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0Q5JCN6

Antitoxin

Source ID Structure
AlphaFold DB A0A1L5QT75

References