Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2023331..2023476 | Replicon | chromosome |
| Accession | NZ_CP018701 | ||
| Organism | Klebsiella pneumoniae strain Kp_Goe_827024 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2023367..2023469 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2023331..2023476 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BB784_RS10230 | 2018461..2020521 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| BB784_RS10240 | 2020525..2021184 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| BB784_RS10245 | 2021263..2021493 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| BB784_RS10250 | 2021606..2021980 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| BB784_RS10255 | 2021984..2022853 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| BB784_RS10260 | 2022870..2023208 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2023331..2023476 | - | 146 | - | - | Antitoxin |
| - | 2023367..2023469 | + | 103 | - | - | Toxin |
| BB784_RS32170 | 2023845..2023988 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| BB784_RS10275 | 2024093..2025061 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| BB784_RS10280 | 2025218..2025871 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| BB784_RS10285 | 2025868..2026059 | - | 192 | WP_002911395.1 | YebW family protein | - |
| BB784_RS10290 | 2026157..2026396 | - | 240 | WP_002911393.1 | YebV family protein | - |
| BB784_RS10295 | 2026512..2027945 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T70275 NZ_CP018701:2023367-2023469 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT70275 NZ_CP018701:c2023476-2023331 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
