Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1947324..1947469 Replicon chromosome
Accession NZ_CP018692
Organism Klebsiella pneumoniae strain Kp_Goe_821588

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1947360..1947462 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1947324..1947469 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BB749_RS09925 1942454..1944514 + 2061 WP_004151449.1 oligopeptidase B -
BB749_RS09935 1944518..1945177 - 660 WP_032425085.1 exodeoxyribonuclease X -
BB749_RS09940 1945256..1945486 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BB749_RS09945 1945599..1945973 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BB749_RS09950 1945977..1946846 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
BB749_RS09955 1946863..1947201 + 339 WP_016529031.1 YebY family protein -
- 1947324..1947469 - 146 - - Antitoxin
- 1947360..1947462 + 103 - - Toxin
BB749_RS29805 1947837..1947980 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BB749_RS09970 1948085..1949053 - 969 WP_004151446.1 VirK/YbjX family protein -
BB749_RS09975 1949210..1949863 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
BB749_RS09980 1949860..1950051 - 192 WP_002911395.1 YebW family protein -
BB749_RS09985 1950149..1950388 - 240 WP_002911393.1 YebV family protein -
BB749_RS09990 1950504..1951937 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T70233 NZ_CP018692:1947360-1947462 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT70233 NZ_CP018692:c1947469-1947324 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References