Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022267..2022412 | Replicon | chromosome |
| Accession | NZ_CP018686 | ||
| Organism | Klebsiella pneumoniae strain Kp_Goe_149473 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022303..2022405 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022267..2022412 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BB750_RS10235 | 2017397..2019457 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| BB750_RS10245 | 2019461..2020120 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| BB750_RS10250 | 2020199..2020429 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| BB750_RS10255 | 2020542..2020916 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| BB750_RS10260 | 2020920..2021789 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| BB750_RS10265 | 2021806..2022144 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2022267..2022412 | - | 146 | - | - | Antitoxin |
| - | 2022303..2022405 | + | 103 | - | - | Toxin |
| BB750_RS32145 | 2022781..2022924 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| BB750_RS10280 | 2023029..2023997 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| BB750_RS10285 | 2024154..2024807 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| BB750_RS10290 | 2024804..2024995 | - | 192 | WP_002911395.1 | YebW family protein | - |
| BB750_RS10295 | 2025093..2025332 | - | 240 | WP_002911393.1 | YebV family protein | - |
| BB750_RS10300 | 2025448..2026881 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T70211 NZ_CP018686:2022303-2022405 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT70211 NZ_CP018686:c2022412-2022267 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
