Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 748785..748930 Replicon chromosome
Accession NZ_CP018676
Organism Klebsiella pneumoniae strain CAV1217

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 748792..748894 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 748785..748930 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AGE86_RS05740 744317..745750 + 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AGE86_RS05745 745866..746105 + 240 WP_002911393.1 YebV family protein -
AGE86_RS05750 746203..746394 + 192 WP_002911395.1 YebW family protein -
AGE86_RS05755 746391..747044 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
AGE86_RS05760 747201..748169 + 969 WP_004151446.1 VirK/YbjX family protein -
AGE86_RS27835 748274..748417 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 748785..748930 + 146 - - Antitoxin
- 748792..748894 - 103 - - Toxin
AGE86_RS05770 749053..749391 - 339 WP_016529031.1 YebY family protein -
AGE86_RS05775 749408..750277 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AGE86_RS05780 750281..750655 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AGE86_RS05785 750768..750998 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AGE86_RS05790 751077..751736 + 660 WP_032425085.1 exodeoxyribonuclease X -
AGE86_RS05795 751740..753800 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T70181 NZ_CP018676:c748894-748792 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT70181 NZ_CP018676:748785-748930 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References