Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3876535..3876896 Replicon chromosome
Accession NZ_CP018475
Organism Xanthomonas perforans strain LH3

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BJD13_RS18925 Protein ID WP_005914328.1
Coordinates 3876762..3876896 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0G8WVL8
Locus tag BJD13_RS18920 Protein ID WP_008576433.1
Coordinates 3876535..3876687 (+) Length 51 a.a.

Genomic Context

BJD13_RS18915BJD13_RS18920BJD13_RS18925BJD13_RS18930BJD13_RS18935BJD13_RS18940BJD13_RS18890BJD13_RS18895BJD13_RS18900BJD13_RS18905BJD13_RS18910
Location: 3875505..3876428 (924 bp)
Type: Others
Protein ID: WP_008576436.1
Location: 3876535..3876687 (153 bp)
Type: Antitoxin
Protein ID: WP_008576433.1
Location: 3876762..3876896 (135 bp)
Type: Toxin
Protein ID: WP_005914328.1
Location: 3877124..3877333 (210 bp)
Type: Others
Protein ID: WP_003486601.1
Location: 3877500..3878789 (1290 bp)
Type: Others
Protein ID: WP_008576429.1
Location: 3878840..3879862 (1023 bp)
Type: Others
Protein ID: WP_046932138.1
Location: 3871607..3872287 (681 bp)
Type: Others
Protein ID: WP_008576441.1
Location: 3872756..3873298 (543 bp)
Type: Others
Protein ID: WP_003486615.1
Location: 3873295..3874212 (918 bp)
Type: Others
Protein ID: WP_008576439.1
Location: 3874309..3874668 (360 bp)
Type: Others
Protein ID: WP_003486613.1
Location: 3874732..3875184 (453 bp)
Type: Others
Protein ID: WP_008576438.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BJD13_RS188903871607..3872287-681WP_008576441.1dTMP kinase-
BJD13_RS188953872756..3873298-543WP_003486615.1GTPase-
BJD13_RS189003873295..3874212-918WP_008576439.1hypothetical protein-
BJD13_RS189053874309..3874668-360WP_003486613.1hypothetical protein-
BJD13_RS189103874732..3875184-453WP_008576438.1roadblock/LC7 domain-containing protein-
BJD13_RS189153875505..3876428+924WP_008576436.1arginase-
BJD13_RS189203876535..3876687+153WP_008576433.1entericidin A/B family lipoproteinAntitoxin
BJD13_RS189253876762..3876896+135WP_005914328.1entericidin A/B family lipoproteinToxin
BJD13_RS189303877124..3877333+210WP_003486601.1CsbD family protein-
BJD13_RS189353877500..3878789+1290WP_008576429.1tryptophan--tRNA ligase-
BJD13_RS189403878840..3879862+1023WP_046932138.1MBL fold metallo-hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70083 WP_005914328.1 NZ_CP018475:3876762-3876896 [Xanthomonas perforans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70083 NZ_CP018475:3876762-3876896 [Xanthomonas perforans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5137.08 Da        Isoelectric Point: 8.2782

>AT70083 WP_008576433.1 NZ_CP018475:3876535-3876687 [Xanthomonas perforans]
MKRLLTLMVLALFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70083 NZ_CP018475:3876535-3876687 [Xanthomonas perforans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGCCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3G2W7U6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0G8WVL8

References