70083

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3876535..3876896 Replicon chromosome
Accession NZ_CP018475
Organism Xanthomonas perforans strain LH3

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BJD13_RS18925 Protein ID WP_005914328.1
Coordinates 3876762..3876896 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0G8WVL8
Locus tag BJD13_RS18920 Protein ID WP_008576433.1
Coordinates 3876535..3876687 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD13_RS18890 3871607..3872287 - 681 WP_008576441.1 dTMP kinase -
BJD13_RS18895 3872756..3873298 - 543 WP_003486615.1 GTPase -
BJD13_RS18900 3873295..3874212 - 918 WP_008576439.1 hypothetical protein -
BJD13_RS18905 3874309..3874668 - 360 WP_003486613.1 hypothetical protein -
BJD13_RS18910 3874732..3875184 - 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
BJD13_RS18915 3875505..3876428 + 924 WP_008576436.1 arginase -
BJD13_RS18920 3876535..3876687 + 153 WP_008576433.1 entericidin A/B family lipoprotein Antitoxin
BJD13_RS18925 3876762..3876896 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BJD13_RS18930 3877124..3877333 + 210 WP_003486601.1 CsbD family protein -
BJD13_RS18935 3877500..3878789 + 1290 WP_008576429.1 tryptophan--tRNA ligase -
BJD13_RS18940 3878840..3879862 + 1023 WP_046932138.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70083 WP_005914328.1 NZ_CP018475:3876762-3876896 [Xanthomonas perforans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70083 NZ_CP018475:3876762-3876896 [Xanthomonas perforans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5137.08 Da        Isoelectric Point: 8.2782

>AT70083 WP_008576433.1 NZ_CP018475:3876535-3876687 [Xanthomonas perforans]
MKRLLTLMVLALFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70083 NZ_CP018475:3876535-3876687 [Xanthomonas perforans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGCCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8WVL8

References