Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3323746..3324293 Replicon chromosome
Accession NZ_CP018475
Organism Xanthomonas perforans strain LH3

Toxin (Protein)


Gene name relE Uniprot ID A0A0G9C4Q2
Locus tag BJD13_RS16615 Protein ID WP_008574054.1
Coordinates 3323746..3324048 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q3BZM5
Locus tag BJD13_RS16620 Protein ID WP_008574056.1
Coordinates 3324036..3324293 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD13_RS16585 3319075..3319683 + 609 WP_008574046.1 NAD(P)H-dependent oxidoreductase -
BJD13_RS16590 3319921..3320631 - 711 WP_008574047.1 hypothetical protein -
BJD13_RS16595 3320831..3321742 - 912 WP_033478804.1 LysR family transcriptional regulator -
BJD13_RS16600 3321868..3322605 + 738 WP_008574050.1 SDR family oxidoreductase -
BJD13_RS16605 3322665..3323564 + 900 WP_008574052.1 SDR family NAD(P)-dependent oxidoreductase -
BJD13_RS16615 3323746..3324048 - 303 WP_008574054.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BJD13_RS16620 3324036..3324293 - 258 WP_008574056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BJD13_RS16625 3324359..3325021 - 663 WP_008574057.1 hemolysin III family protein -
BJD13_RS16630 3325199..3327694 + 2496 WP_008574058.1 DEAD/DEAH box helicase -
BJD13_RS16635 3327691..3329148 + 1458 WP_008574059.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3313891..3324293 10402


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11522.33 Da        Isoelectric Point: 9.1267

>T70082 WP_008574054.1 NZ_CP018475:c3324048-3323746 [Xanthomonas perforans]
MAEIIWSVPALADLDAIADDIAIDNAPAAAAALVKWVLPQVERLIEHPDSGSRPQELQRSRYRQIVEPPCRVFYRVDGQR
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

>T70082 NZ_CP018475:c3324048-3323746 [Xanthomonas perforans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACGACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTCGAGCGATTGATTGAACACCCGGACAGCGGAAGCCGGC
CACAGGAACTCCAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGC
ATCGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9686.18 Da        Isoelectric Point: 10.0780

>AT70082 WP_008574056.1 NZ_CP018475:c3324293-3324036 [Xanthomonas perforans]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK

Download         Length: 258 bp

>AT70082 NZ_CP018475:c3324293-3324036 [Xanthomonas perforans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G9C4Q2

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2WGS6

References