Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2845209..2845574 Replicon chromosome
Accession NZ_CP018470
Organism Xanthomonas vesicatoria strain LM159

Toxin (Protein)


Gene name EcnB Uniprot ID F0B9H9
Locus tag BI313_RS13805 Protein ID WP_005989324.1
Coordinates 2845209..2845343 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1L5QT75
Locus tag BI313_RS13810 Protein ID WP_039421598.1
Coordinates 2845422..2845574 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI313_RS13790 2842187..2843125 - 939 WP_039423874.1 MBL fold metallo-hydrolase -
BI313_RS13795 2843325..2844614 - 1290 WP_039421599.1 tryptophan--tRNA ligase -
BI313_RS13800 2844784..2844993 - 210 WP_005989323.1 CsbD family protein -
BI313_RS13805 2845209..2845343 - 135 WP_005989324.1 entericidin A/B family lipoprotein Toxin
BI313_RS13810 2845422..2845574 - 153 WP_039421598.1 entericidin A/B family lipoprotein Antitoxin
BI313_RS13815 2845684..2846607 - 924 WP_039421597.1 arginase -
BI313_RS13820 2846927..2847379 + 453 WP_039421596.1 roadblock/LC7 domain-containing protein -
BI313_RS13825 2847448..2847807 + 360 WP_005989340.1 hypothetical protein -
BI313_RS13830 2847902..2848819 + 918 WP_039421595.1 hypothetical protein -
BI313_RS13835 2848816..2849355 + 540 WP_005989344.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4523.37 Da        Isoelectric Point: 9.3487

>T70079 WP_005989324.1 NZ_CP018470:c2845343-2845209 [Xanthomonas vesicatoria]
MKRAIVLLVLSMFSVAMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70079 NZ_CP018470:c2845343-2845209 [Xanthomonas vesicatoria]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTCTCGGTCGCGATGTTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGTAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5141.09 Da        Isoelectric Point: 8.2782

>AT70079 WP_039421598.1 NZ_CP018470:c2845574-2845422 [Xanthomonas vesicatoria]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT70079 NZ_CP018470:c2845574-2845422 [Xanthomonas vesicatoria]
ATGAAGCGACTGCTGACACTAATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACTGGTTGCAACACCATGGCTGGCGC
CGGCAAGGACATGCAAGGTGCGGGCGACAAGGTCGAAAAGACCGCCGATAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0Q5JCN6

Antitoxin

Source ID Structure
AlphaFold DB A0A1L5QT75

References