70078

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 5049305..5049666 Replicon chromosome
Accession NZ_CP018467
Organism Xanthomonas euvesicatoria strain LMG930

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag BJD11_RS24835 Protein ID WP_005914328.1
Coordinates 5049532..5049666 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q3BN31
Locus tag BJD11_RS24830 Protein ID WP_011348912.1
Coordinates 5049305..5049457 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD11_RS24795 5044375..5045055 - 681 WP_011348915.1 dTMP kinase -
BJD11_RS24805 5045526..5046068 - 543 WP_039418666.1 GTPase -
BJD11_RS24810 5046065..5046982 - 918 WP_008576439.1 hypothetical protein -
BJD11_RS24815 5047079..5047438 - 360 WP_003486613.1 hypothetical protein -
BJD11_RS24820 5047502..5047954 - 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
BJD11_RS24825 5048275..5049198 + 924 WP_008576436.1 arginase -
BJD11_RS24830 5049305..5049457 + 153 WP_011348912.1 entericidin A/B family lipoprotein Antitoxin
BJD11_RS24835 5049532..5049666 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
BJD11_RS24840 5049894..5050103 + 210 WP_003486601.1 CsbD family protein -
BJD11_RS24845 5050270..5051559 + 1290 WP_011348911.1 tryptophan--tRNA ligase -
BJD11_RS24850 5051610..5052632 + 1023 WP_011348910.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T70078 WP_005914328.1 NZ_CP018467:5049532-5049666 [Xanthomonas euvesicatoria]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T70078 NZ_CP018467:5049532-5049666 [Xanthomonas euvesicatoria]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCGGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5123.06 Da        Isoelectric Point: 8.2782

>AT70078 WP_011348912.1 NZ_CP018467:5049305-5049457 [Xanthomonas euvesicatoria]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT70078 NZ_CP018467:5049305-5049457 [Xanthomonas euvesicatoria]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCAGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2W7I0

References