Detailed information of TA system TA070077

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4651406..4652985
• Replicon: chromosome
• Accession: NZ_CP018467
• Organism: Xanthomonas euvesicatoria strain LMG930

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: BJD11_RS23180
• Protein ID: WP_129111554.1
• Coordinates: 4651720..4652985 (-)
• Length: 422 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: Q3BM53
• Locus tag: BJD11_RS23175
• Protein ID: WP_011349168.1
• Coordinates: 4651406..4651702 (-)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJD11_RS23145	4646798..4647316	+	519	WP_041855098.1	hypothetical protein	-
BJD11_RS23150	4647682..4648422	-	741	WP_011349173.1	glucose 1-dehydrogenase	-
BJD11_RS23155	4648506..4649078	+	573	WP_041855097.1	TetR/AcrR family transcriptional regulator	-
BJD11_RS23160	4649195..4649764	+	570	WP_011349171.1	TetR/AcrR family transcriptional regulator	-
BJD11_RS23165	4649828..4650304	+	477	WP_011349170.1	nuclear transport factor 2 family protein	-
BJD11_RS23170	4650474..4650883	-	410	Protein_3895	hypothetical protein	-
BJD11_RS23175	4651406..4651702	-	297	WP_011349168.1	hypothetical protein	Antitoxin
BJD11_RS23180	4651720..4652985	-	1266	WP_129111554.1	zeta toxin family protein	Toxin
BJD11_RS23185	4653133..4653558	-	426	Protein_3898	restriction endonuclease	-
BJD11_RS23195	4653624..4654756	+	1133	WP_087942069.1	IS3-like element IS476 family transposase	-
BJD11_RS23200	4655212..4656144	-	933	WP_011349157.1	hypothetical protein	-
BJD11_RS23205	4656161..4656454	-	294	WP_031425188.1	hypothetical protein	-
BJD11_RS23210	4657226..4657786	+	561	WP_074038902.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4646492..4663872	17380

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (151-291)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 422 a.a.
• Molecular weight: 45183.56 Da
• Isoelectric Point: 6.1927

>T70077 WP_129111554.1 NZ_CP018467:c4652985-4651720 [Xanthomonas euvesicatoria]
IKNKIGIAGTAGLFTSHVPFDDAESKGVQAESSQAAPEYKFQTQLDNLPARPASSKSSNTTHAYVHASPPHSVPIAGAST
AAVTHQQATQLKGTDELYGLGNLPSSGPGRWEYLANPENWHPERRKLHEKLLDEARSSALTLAESLERDGCQPTLFALRG
NTATGKTRIATKKIPALAAALEKTGGKGCINPDVFKSSLAKSEAGAKIFSSAQVHNESCFLADHFEDGLRSQRTGSGAIA
SIVVDKRLARAYEIDSYIELAKETGRKVELCDIDAPLENSLTGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMSVIDRFI
ADPSLGNYRLFGTAEDGKKVMVASVMGGELSVEDADLYEKITSPQSSVTGDLADKIIDNELIDRLTNNIDDPERAANTRA
ALEKYNGKSWSAALAAHSELI

Nucleotide

• Length: 1266 bp

>T70077 NZ_CP018467:c4652985-4651720 [Xanthomonas euvesicatoria]
ATAAAAAACAAGATAGGCATTGCTGGCACAGCCGGGCTTTTTACTTCTCATGTTCCTTTCGATGACGCAGAATCCAAAGG
CGTCCAAGCTGAGTCATCACAAGCGGCGCCGGAGTATAAATTCCAGACCCAGCTTGATAATTTGCCAGCTAGACCCGCTA
GTTCGAAGAGCAGCAACACCACTCATGCTTATGTTCATGCATCGCCGCCGCATTCGGTGCCGATCGCAGGTGCATCGACC
GCCGCGGTGACACATCAACAGGCTACTCAGCTTAAAGGCACCGATGAGTTATATGGTTTGGGCAACCTCCCATCTTCTGG
TCCGGGGCGATGGGAGTATCTGGCGAATCCGGAGAACTGGCATCCGGAGCGCCGTAAGTTGCACGAAAAGCTATTAGATG
AAGCACGATCTTCGGCCTTGACCCTGGCAGAATCTCTTGAGCGCGATGGCTGCCAACCGACATTGTTTGCGTTGCGCGGA
AACACTGCCACGGGTAAGACGCGGATAGCCACAAAAAAAATTCCAGCTCTCGCCGCAGCTCTGGAGAAGACAGGTGGGAA
AGGTTGCATCAATCCAGATGTATTCAAGAGTTCGCTTGCGAAGTCGGAGGCCGGCGCCAAGATATTTAGCTCGGCGCAAG
TTCATAACGAATCATGTTTTCTTGCTGACCATTTTGAAGACGGGCTTCGCTCTCAAAGGACGGGCAGCGGTGCAATCGCT
AGCATTGTTGTCGACAAGCGCTTGGCAAGGGCGTACGAAATCGACAGCTATATAGAACTAGCCAAAGAAACAGGTCGAAA
AGTTGAATTGTGCGATATCGATGCACCCCTTGAGAATTCTTTGACGGGAGTTTTGCAACGGAAACCTGAAGGTGAAGATC
CTAGGCCTCCTTACCCTGTAGTCTCGAGTGGATTTGTGGCCGTACGAAGCAATAGAATGAGTGTGATAGACAGGTTCATC
GCCGATCCGAGCCTGGGAAACTATCGACTATTCGGAACAGCCGAGGATGGTAAGAAGGTCATGGTTGCTAGCGTCATGGG
CGGTGAGTTGAGTGTAGAGGATGCTGATTTATATGAAAAGATAACGTCCCCGCAGTCCTCGGTTACCGGTGATTTGGCTG
ATAAGATAATCGACAATGAATTGATTGATCGTCTGACAAATAATATAGATGATCCCGAGCGCGCGGCGAATACGCGAGCC
GCGCTGGAAAAATATAACGGCAAGTCGTGGTCGGCCGCGCTAGCTGCTCATAGCGAGCTAATTTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11347.05 Da
• Isoelectric Point: 8.0069

>AT70077 WP_011349168.1 NZ_CP018467:c4651702-4651406 [Xanthomonas euvesicatoria]
MKTLKGAEALEFHKKLKGRNEALHASDIASALVRADAVGKERFDLEELEKLCYTSSAGRLTDVKERRDIYERMYYVEYPK
IMTLKEFARIVETLSSWS

Nucleotide

• Length: 297 bp

>AT70077 NZ_CP018467:c4651702-4651406 [Xanthomonas euvesicatoria]
ATGAAAACTTTGAAAGGCGCAGAGGCGCTCGAATTCCATAAGAAGCTTAAGGGACGCAATGAAGCCTTACATGCTTCCGA
TATCGCGTCAGCATTAGTACGCGCCGATGCCGTCGGCAAGGAACGGTTTGATCTCGAGGAACTGGAAAAACTTTGCTATA
CCAGTAGTGCGGGGCGCCTTACTGATGTGAAAGAGCGCCGCGACATATATGAGCGGATGTACTACGTCGAGTATCCTAAA
ATTATGACGTTAAAGGAATTTGCTCGTATCGTTGAGACACTTTCCTCTTGGTCATGA

Structures

Antitoxin

• AlphaFold DB: Q3BM53