Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4508216..4508763 Replicon chromosome
Accession NZ_CP018467
Organism Xanthomonas euvesicatoria strain LMG930

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2W0H9
Locus tag BJD11_RS22555 Protein ID WP_039418332.1
Coordinates 4508216..4508518 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q3BZM5
Locus tag BJD11_RS22560 Protein ID WP_008574056.1
Coordinates 4508506..4508763 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD11_RS22530 4503578..4505143 - 1566 WP_011345818.1 ATP-binding protein -
BJD11_RS22535 4506069..4506212 - 144 Protein_3779 LysR family transcriptional regulator -
BJD11_RS22540 4506337..4507074 + 738 WP_008574050.1 SDR family oxidoreductase -
BJD11_RS22545 4507134..4508033 + 900 WP_011345816.1 SDR family NAD(P)-dependent oxidoreductase -
BJD11_RS22555 4508216..4508518 - 303 WP_039418332.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BJD11_RS22560 4508506..4508763 - 258 WP_008574056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BJD11_RS22565 4508829..4509491 - 663 WP_011345814.1 hemolysin III family protein -
BJD11_RS22570 4509669..4512164 + 2496 WP_011345813.1 DEAD/DEAH box helicase -
BJD11_RS22575 4512161..4513624 + 1464 WP_011345812.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11523.36 Da        Isoelectric Point: 9.0231

>T70076 WP_039418332.1 NZ_CP018467:c4508518-4508216 [Xanthomonas euvesicatoria]
MAEIIWSVPALADLDAIADYIAIDNAPAAAAALVKWVLPQVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQH
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

>T70076 NZ_CP018467:c4508518-4508216 [Xanthomonas euvesicatoria]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCGGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTTGAGCAATTAATTGAACACCCCGACAGCGGAAGCCGGC
CACAGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCAC
ATTGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9686.18 Da        Isoelectric Point: 10.0780

>AT70076 WP_008574056.1 NZ_CP018467:c4508763-4508506 [Xanthomonas euvesicatoria]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK

Download         Length: 258 bp

>AT70076 NZ_CP018467:c4508763-4508506 [Xanthomonas euvesicatoria]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W0H9

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2WGS6

References