Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3312612..3312757 Replicon chromosome
Accession NZ_CP018437
Organism Klebsiella pneumoniae strain MNCRE53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3312619..3312721 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3312612..3312757 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTE50_RS19655 3308144..3309577 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BTE50_RS19660 3309693..3309932 + 240 WP_002911393.1 YebV family protein -
BTE50_RS19665 3310030..3310221 + 192 WP_002911395.1 YebW family protein -
BTE50_RS19670 3310218..3310871 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
BTE50_RS19675 3311028..3311996 + 969 WP_004151446.1 VirK/YbjX family protein -
BTE50_RS32780 3312101..3312244 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3312612..3312757 + 146 - - Antitoxin
- 3312619..3312721 - 103 - - Toxin
BTE50_RS19690 3312880..3313218 - 339 WP_002911404.1 YebY family protein -
BTE50_RS19695 3313235..3314104 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
BTE50_RS19700 3314108..3314482 - 375 WP_004151448.1 CopC domain-containing protein YobA -
BTE50_RS19705 3314595..3314825 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BTE50_RS19710 3314904..3315563 + 660 WP_002911407.1 exodeoxyribonuclease X -
BTE50_RS19720 3315567..3317627 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T69980 NZ_CP018437:c3312721-3312619 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT69980 NZ_CP018437:3312612-3312757 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References