Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3275952..3276097 Replicon chromosome
Accession NZ_CP018428
Organism Klebsiella pneumoniae strain MNCRE78

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3275959..3276061 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3275952..3276097 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTE52_RS17470 3271484..3272917 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BTE52_RS17475 3273033..3273272 + 240 WP_002911393.1 YebV family protein -
BTE52_RS17480 3273370..3273561 + 192 WP_002911395.1 YebW family protein -
BTE52_RS17485 3273558..3274211 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
BTE52_RS17490 3274368..3275336 + 969 WP_004151446.1 VirK/YbjX family protein -
BTE52_RS32535 3275441..3275584 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3275952..3276097 + 146 - - Antitoxin
- 3275959..3276061 - 103 - - Toxin
BTE52_RS17505 3276220..3276558 - 339 WP_002911404.1 YebY family protein -
BTE52_RS17510 3276575..3277444 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
BTE52_RS17515 3277448..3277822 - 375 WP_004151448.1 CopC domain-containing protein YobA -
BTE52_RS17520 3277935..3278165 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BTE52_RS17525 3278244..3278903 + 660 WP_002911407.1 exodeoxyribonuclease X -
BTE52_RS17535 3278907..3280967 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T69960 NZ_CP018428:c3276061-3275959 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT69960 NZ_CP018428:3275952-3276097 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References