Detailed information of TA system TA069929

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 378751..379240
• Replicon: chromosome
• Accession: NZ_CP018420
• Organism: Pseudomonas veronii strain R02

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1D3JQH6
• Locus tag: PverR02_RS01715
• Protein ID: WP_032805156.1
• Coordinates: 378929..379240 (+)
• Length: 104 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PverR02_RS01710
• Protein ID: WP_079444974.1
• Coordinates: 378751..378942 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PverR02_RS01690	374246..375019	-	774	WP_017849951.1	ABC transporter ATP-binding protein	-
PverR02_RS01695	375575..376966	+	1392	WP_017849950.1	GABA permease	-
PverR02_RS01700	377107..377520	-	414	WP_046385011.1	hypothetical protein	-
PverR02_RS01705	377590..378537	-	948	WP_079442657.1	alpha/beta fold hydrolase	-
PverR02_RS01710	378751..378942	+	192	WP_079444974.1	antitoxin	Antitoxin
PverR02_RS01715	378929..379240	+	312	WP_032805156.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PverR02_RS01720	379282..380256	+	975	WP_079442658.1	arsenic resistance protein	-
PverR02_RS01725	380335..381942	+	1608	WP_017849945.1	glycosyltransferase family 39 protein	-
PverR02_RS01735	382265..382537	-	273	WP_017849944.1	oxidative damage protection protein	-
PverR02_RS01740	382534..383601	-	1068	WP_079442659.1	A/G-specific adenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 104 a.a.
• Molecular weight: 11782.70 Da
• Isoelectric Point: 7.1408

>T69929 WP_032805156.1 NZ_CP018420:378929-379240 [Pseudomonas veronii]
VLLVKWRPEAIVALIEIIDYIEQYNPVAAVSLHQTIVVAAEGLSLMPYGFKHGRLSGTREMVVHPNYLVVYRVTEHVEIV
MVLHTRQEYPRDVIGPHHSTSRQ

Nucleotide

• Length: 312 bp

>T69929 NZ_CP018420:378929-379240 [Pseudomonas veronii]
GTGCTTCTCGTTAAATGGCGACCTGAGGCTATTGTCGCCCTGATCGAGATCATTGATTACATCGAGCAGTACAACCCGGT
TGCCGCCGTCTCGCTGCACCAAACTATTGTGGTTGCCGCCGAGGGGTTGTCCCTGATGCCATACGGATTCAAGCACGGTC
GCTTGTCTGGTACTCGGGAAATGGTTGTTCATCCAAACTACCTGGTGGTCTATCGGGTGACGGAGCACGTTGAGATAGTG
ATGGTGTTACACACTCGCCAGGAATATCCCAGGGATGTGATCGGGCCACACCACTCGACCTCACGCCAGTAG

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7314.20 Da
• Isoelectric Point: 5.8317

>AT69929 WP_079444974.1 NZ_CP018420:378751-378942 [Pseudomonas veronii]
MSIPRTPIVSEFETEEQAASYDRWFRAKVQASIDDPRPSIPHDQAMAEVEKVLEERRKARASR

Nucleotide

• Length: 192 bp

>AT69929 NZ_CP018420:378751-378942 [Pseudomonas veronii]
ATGAGCATTCCACGTACTCCCATCGTTTCGGAGTTTGAAACAGAAGAGCAAGCTGCCAGCTACGACCGTTGGTTTCGTGC
CAAGGTGCAGGCTTCAATTGACGATCCTCGTCCTAGTATTCCGCACGATCAGGCGATGGCTGAAGTCGAGAAGGTGCTGG
AAGAGAGGCGCAAGGCTCGTGCTTCTCGTTAA

Structures

Toxin

• AlphaFold DB: A0A1D3JQH6