Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1955895..1956040 Replicon chromosome
Accession NZ_CP018364
Organism Klebsiella pneumoniae strain Kp_Goe_62629

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1955931..1956033 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1955895..1956040 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BB790_RS10090 1951025..1953085 + 2061 WP_004151449.1 oligopeptidase B -
BB790_RS10100 1953089..1953748 - 660 WP_002911407.1 exodeoxyribonuclease X -
BB790_RS10105 1953827..1954057 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BB790_RS10110 1954170..1954544 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BB790_RS10115 1954548..1955417 + 870 WP_019725445.1 copper homeostasis membrane protein CopD -
BB790_RS10120 1955434..1955772 + 339 WP_002911404.1 YebY family protein -
- 1955895..1956040 - 146 - - Antitoxin
- 1955931..1956033 + 103 - - Toxin
BB790_RS31490 1956408..1956551 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BB790_RS10135 1956656..1957624 - 969 WP_004151446.1 VirK/YbjX family protein -
BB790_RS10140 1957781..1958434 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
BB790_RS10145 1958431..1958622 - 192 WP_002911395.1 YebW family protein -
BB790_RS10150 1958720..1958959 - 240 WP_002911393.1 YebV family protein -
BB790_RS10155 1959075..1960508 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T69853 NZ_CP018364:1955931-1956033 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT69853 NZ_CP018364:c1956040-1955895 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References