Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2576691..2576836 Replicon chromosome
Accession NZ_CP018356
Organism Klebsiella pneumoniae strain CAV1453

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2576698..2576800 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2576691..2576836 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AGG69_RS15300 2572223..2573656 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AGG69_RS15305 2573772..2574011 + 240 WP_002911393.1 YebV family protein -
AGG69_RS15310 2574109..2574300 + 192 WP_002911395.1 YebW family protein -
AGG69_RS15315 2574297..2574950 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
AGG69_RS15320 2575107..2576075 + 969 WP_004151446.1 VirK/YbjX family protein -
AGG69_RS30385 2576180..2576323 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2576691..2576836 + 146 - - Antitoxin
- 2576698..2576800 - 103 - - Toxin
AGG69_RS15335 2576959..2577297 - 339 WP_002911404.1 YebY family protein -
AGG69_RS15340 2577314..2578183 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AGG69_RS15345 2578187..2578561 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AGG69_RS15350 2578674..2578904 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AGG69_RS15355 2578983..2579642 + 660 WP_002911407.1 exodeoxyribonuclease X -
AGG69_RS15365 2579646..2581706 - 2061 WP_032422099.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T69805 NZ_CP018356:c2576800-2576698 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT69805 NZ_CP018356:2576691-2576836 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References