Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 213071..213216 Replicon chromosome
Accession NZ_CP018352
Organism Klebsiella pneumoniae strain CAV1417

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 213107..213209 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 213071..213216 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AGG42_RS02945 208201..210261 + 2061 WP_004151449.1 oligopeptidase B -
AGG42_RS02950 210265..210924 - 660 WP_032425085.1 exodeoxyribonuclease X -
AGG42_RS02955 211003..211233 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AGG42_RS02960 211346..211720 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AGG42_RS02965 211724..212593 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AGG42_RS02970 212610..212948 + 339 WP_016529031.1 YebY family protein -
- 213071..213216 - 146 - - Antitoxin
- 213107..213209 + 103 - - Toxin
AGG42_RS28715 213584..213727 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AGG42_RS02980 213832..214800 - 969 WP_004151446.1 VirK/YbjX family protein -
AGG42_RS02985 214957..215610 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AGG42_RS02990 215607..215798 - 192 WP_002911395.1 YebW family protein -
AGG42_RS02995 215896..216135 - 240 WP_002911393.1 YebV family protein -
AGG42_RS03000 216251..217684 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T69781 NZ_CP018352:213107-213209 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT69781 NZ_CP018352:c213216-213071 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References