Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1944181..1944326 | Replicon | chromosome |
| Accession | NZ_CP018337 | ||
| Organism | Klebsiella pneumoniae isolate Kp_Goe_154414 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1944217..1944319 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1944181..1944326 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BB788_RS09905 | 1939311..1941371 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| BB788_RS09915 | 1941375..1942034 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| BB788_RS09920 | 1942113..1942343 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| BB788_RS09925 | 1942456..1942830 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| BB788_RS09930 | 1942834..1943703 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| BB788_RS09935 | 1943720..1944058 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1944181..1944326 | - | 146 | - | - | Antitoxin |
| - | 1944217..1944319 | + | 103 | - | - | Toxin |
| BB788_RS31715 | 1944695..1944838 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| BB788_RS09950 | 1944943..1945911 | - | 969 | WP_073558112.1 | DUF535 family protein | - |
| BB788_RS09955 | 1946068..1946721 | + | 654 | WP_020802220.1 | protein-serine/threonine phosphatase | - |
| BB788_RS09960 | 1946718..1946909 | - | 192 | WP_002911395.1 | YebW family protein | - |
| BB788_RS09965 | 1947007..1947246 | - | 240 | WP_002911393.1 | YebV family protein | - |
| BB788_RS09970 | 1947362..1948795 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T69754 NZ_CP018337:1944217-1944319 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT69754 NZ_CP018337:c1944326-1944181 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
