Detailed information of TA system TA069748

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3221327..3221980
• Replicon: chromosome
• Accession: NZ_CP018332
• Organism: Acinetobacter baumannii strain A1296

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A9E9PBS3
• Locus tag: BS103_RS15460
• Protein ID: WP_002096593.1
• Coordinates: 3221327..3221716 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: BS103_RS15465
• Protein ID: WP_001288210.1
• Coordinates: 3221723..3221980 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BS103_RS15445	3216445..3218640	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
BS103_RS15450	3218828..3219394	-	567	WP_000651536.1	rhombosortase	-
BS103_RS15455	3219472..3220557	-	1086	WP_000049106.1	hypothetical protein	-
BS103_RS15460	3221327..3221716	-	390	WP_002096593.1	hypothetical protein	Toxin
BS103_RS15465	3221723..3221980	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
BS103_RS15470	3222168..3223340	+	1173	WP_001190548.1	acyl-CoA dehydrogenase family protein	-
BS103_RS15475	3223389..3224879	-	1491	WP_004745487.1	NAD(P)/FAD-dependent oxidoreductase	-
BS103_RS15480	3225061..3225438	-	378	WP_001216380.1	50S ribosomal protein L17	-
BS103_RS15485	3225457..3226464	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15677.99 Da
• Isoelectric Point: 10.3890

>T69748 WP_002096593.1 NZ_CP018332:c3221716-3221327 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T69748 NZ_CP018332:c3221716-3221327 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCACGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGTAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT69748 WP_001288210.1 NZ_CP018332:c3221980-3221723 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT69748 NZ_CP018332:c3221980-3221723 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7