Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4259717..4259988 Replicon chromosome
Accession NZ_CP018323
Organism Escherichia coli strain KSC9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4259755..4259858 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4259717..4259988 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BS635_RS21955 4256874..4258313 + 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BS635_RS21960 4258431..4258667 + 237 WP_001295499.1 DUF1480 family protein -
BS635_RS21965 4258772..4258963 + 192 WP_001296140.1 YebW family protein -
BS635_RS21970 4258964..4259620 - 657 WP_000812734.1 protein-serine/threonine phosphatase -
- 4259717..4259988 + 272 - - Antitoxin
- 4259755..4259858 - 104 - - Toxin
BS635_RS21975 4260016..4260357 - 342 WP_000976492.1 YebY family protein -
BS635_RS21980 4260370..4261242 - 873 WP_000879285.1 copper homeostasis membrane protein CopD -
BS635_RS21985 4261246..4261620 - 375 WP_000204699.1 CopC domain-containing protein YobA -
BS635_RS21990 4261759..4261989 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BS635_RS21995 4262091..4262747 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
BS635_RS22000 4262771..4263433 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T69738 NZ_CP018323:c4259858-4259755 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT69738 NZ_CP018323:4259717-4259988 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References