Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3185708..3187437 Replicon chromosome
Accession NZ_CP018319
Organism Pseudomonas frederiksbergensis strain AS1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag PFAS1_RS14760 Protein ID WP_076029606.1
Coordinates 3186793..3187437 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag PFAS1_RS14755 Protein ID WP_076029605.1
Coordinates 3185708..3186796 (-) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFAS1_RS14745 3183190..3184809 + 1620 WP_076029603.1 DUF2300 domain-containing protein -
PFAS1_RS14750 3184813..3185625 + 813 WP_076029604.1 DUF2135 domain-containing protein -
PFAS1_RS14755 3185708..3186796 - 1089 WP_076029605.1 macro domain-containing protein Antitoxin
PFAS1_RS14760 3186793..3187437 - 645 WP_076029606.1 DUF4433 domain-containing protein Toxin
PFAS1_RS14765 3187434..3188015 - 582 WP_076029607.1 DUF4433 domain-containing protein -
PFAS1_RS14770 3188180..3189100 - 921 WP_076029608.1 restriction endonuclease -
PFAS1_RS14775 3189866..3190618 - 753 WP_074871240.1 helix-turn-helix transcriptional regulator -
PFAS1_RS14780 3190842..3191369 - 528 WP_028620880.1 inorganic diphosphatase -
PFAS1_RS14785 3191483..3192295 - 813 WP_076029609.1 zinc-dependent peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24707.14 Da        Isoelectric Point: 6.2876

>T69717 WP_076029606.1 NZ_CP018319:c3187437-3186793 [Pseudomonas frederiksbergensis]
MNYTSLNPEKALIWRIVHRDNLPWILDNGLHCASSEAQAPQYVNIGNADLIDKRRNRCVPIPPAGVLADYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLYRVEQLGLPFVFTNAHAYPDWTDYYSDLANLGEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYNDAMKECIEQDVAARGLTLSVHARPGWYFQ

Download         Length: 645 bp

>T69717 NZ_CP018319:c3187437-3186793 [Pseudomonas frederiksbergensis]
ATGAACTACACCAGTCTGAATCCAGAGAAGGCTCTGATTTGGCGGATCGTCCACCGCGATAACCTGCCTTGGATTCTGGA
CAATGGGTTGCATTGCGCCAGCTCGGAGGCACAGGCACCGCAGTACGTGAATATTGGCAACGCCGACTTGATCGACAAGC
GCCGCAATCGCTGTGTTCCTATCCCTCCAGCGGGCGTATTGGCCGACTACGTACCCTTCTACTTCACTCCCTTCTCTGTG
ATGATGAAAAACATTCACTCCGGATGGAGCGTTCAGCAACGCAGCAACGATGAGATCGTGATTCTGGTCTCCAGCCTGTA
CCGCGTAGAACAGCTTGGCCTACCATTCGTCTTCACAAATGCACACGCCTACCCGGATTGGACAGACTATTACAGCGACT
TGGCGAATCTCGGCGAGATCGATTGGTCTATCCTTCAACGACGCGACTTCAAACGTGACCCTGATGACCCTCGAAAGATG
GAGCGCTATCAGGCCGAAGCGCTGATTCACCATCACCTACCGATTACAGGACTCCTTGGCATCATGTGCTACAACGATGC
AATGAAAGAATGCATAGAGCAGGACGTGGCCGCTAGAGGCCTGACGTTATCTGTTCATGCGCGTCCGGGATGGTATTTCC
AATGA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40722.77 Da        Isoelectric Point: 6.5049

>AT69717 WP_076029605.1 NZ_CP018319:c3186796-3185708 [Pseudomonas frederiksbergensis]
MIRFTQGNLLEANTEALVNTVNTVGVMGKGIALMFKERFADNYRLYSAACKAGEVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWPEVREQIVDVLSDLDIDVLVFEPSNQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIENLPDTENPLNLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAGISDVIWFDQERKAFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLSQEKVSPTVPAVREA
LKHWDGGAGAAARKSRLFDDPALDIALKRLTSSSFKPVMAVC

Download         Length: 1089 bp

>AT69717 NZ_CP018319:c3186796-3185708 [Pseudomonas frederiksbergensis]
ATGATCAGATTTACCCAGGGCAACCTTCTGGAAGCCAACACTGAAGCCCTCGTCAACACAGTCAATACCGTGGGCGTGAT
GGGCAAAGGTATCGCGCTGATGTTCAAAGAACGCTTCGCGGATAATTACCGTCTGTATTCGGCCGCCTGCAAGGCTGGCG
AGGTAGAGACAGGCAAGGTTCACGTAACGGCAGTCAACGAACTGGACGGCCCTCGCTGGATCGTAAACTTTCCTACCAAA
CGTCACTGGCGATCACCGTCGCAGATGGCGTGGATTACTGAAGGCTTGCACGATCTGCGTCGCTTCCTGATTGAAAACCA
CGTGAAGTCCGTGGCAGTTCCACCGCTAGGTGCGGGCAACGGTGGTTTGAAATGGCCAGAAGTTCGTGAACAGATTGTTG
ATGTACTGAGTGATCTGGATATCGATGTGTTGGTATTCGAACCTTCCAACCAGTATCTGAATGTCGCCAAGCGTAGTGGC
GTGGAAAAGCTCACGCCTGCTCGCGCGCTCATCGCAGAACTGGTCCGACGCTACTGGGTTTTAGGAATGGAATGCAGTCT
GCTTGAGATTCAGAAGCTGGCCTGGTTCCTGGAACGAGCTATAGAGAATCTACCGGACACTGAAAACCCGCTGAACCTTA
AGTTTGTAGCTCATAAATACGGGCCGTACGCCAATCGGTTGGAACATCTGCTCAATAACCTGGATGGAAGCTATCTGCAT
TGCGACAAGCGCATCAGTGATGCAGGTATCAGTGATGTGATCTGGTTTGACCAAGAGCGCAAAGCCTTTTTGCAAACATA
TCTAAAGACAGAGGCCAAGGAGTACTCCCAAGCCTTGGAGCGCACTGCTGAGTTAATCGACGGCTTTGAGTCGCCCTTCG
GCATGGAATTGCTGGCGACGGTCGACTGGTTGCTAAGCCAGGAGAAGGTATCCCCGACCGTCCCTGCCGTACGCGAAGCG
TTGAAGCATTGGGACGGGGGAGCCGGTGCCGCCGCTCGCAAGAGCAGGCTGTTCGACGATCCGGCGCTTGATATTGCACT
CAAACGTCTTACCAGCAGTAGTTTCAAGCCGGTAATGGCTGTCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References