Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1277918..1278465 Replicon chromosome
Accession NZ_CP018312
Organism Vibrio rotiferianus strain B64D1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSZ04_RS15170 Protein ID WP_005448239.1
Coordinates 1278163..1278465 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BSZ04_RS15165 Protein ID WP_088880731.1
Coordinates 1277918..1278175 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSZ04_RS15120 1273433..1273525 + 93 WP_081334116.1 DUF3265 domain-containing protein -
BSZ04_RS15125 1273562..1273912 + 351 WP_088880727.1 hypothetical protein -
BSZ04_RS15130 1274065..1274595 + 531 WP_161493760.1 hypothetical protein -
BSZ04_RS15135 1274610..1274702 + 93 WP_193241297.1 DUF3265 domain-containing protein -
BSZ04_RS15140 1274729..1275139 + 411 WP_088881612.1 hydrolase -
BSZ04_RS15145 1275299..1275982 + 684 WP_088880730.1 SDR family oxidoreductase -
BSZ04_RS15150 1276106..1277332 + 1227 WP_088881613.1 hypothetical protein -
BSZ04_RS15155 1277450..1277665 + 216 WP_029837056.1 hypothetical protein -
BSZ04_RS15160 1277726..1277836 + 111 WP_088881614.1 DUF3265 domain-containing protein -
BSZ04_RS15165 1277918..1278175 + 258 WP_088880731.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BSZ04_RS15170 1278163..1278465 + 303 WP_005448239.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSZ04_RS15175 1278501..1278593 + 93 WP_005448238.1 DUF3265 domain-containing protein -
BSZ04_RS15180 1279049..1279141 + 93 WP_079852366.1 DUF3265 domain-containing protein -
BSZ04_RS15185 1279172..1280299 + 1128 WP_050548321.1 nucleotide-binding protein -
BSZ04_RS15190 1280935..1281024 + 90 WP_071652537.1 DUF3265 domain-containing protein -
BSZ04_RS15195 1281122..1281574 + 453 WP_088880732.1 DUF4065 domain-containing protein -
BSZ04_RS15200 1281555..1282130 + 576 WP_088880733.1 hypothetical protein -
BSZ04_RS15205 1282283..1282633 + 351 WP_088881615.1 hypothetical protein -
BSZ04_RS15210 1282796..1283206 + 411 WP_025613414.1 cytidine deaminase -
BSZ04_RS15215 1283224..1283313 + 90 WP_079766096.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 992555..1301378 308823
- inside Integron - - 1243646..1303220 59574


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11626.50 Da        Isoelectric Point: 4.8951

>T69708 WP_005448239.1 NZ_CP018312:1278163-1278465 [Vibrio rotiferianus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTVFSKVERLEAFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ

Download         Length: 303 bp

>T69708 NZ_CP018312:1278163-1278465 [Vibrio rotiferianus]
ATGGCTGAAATAATCTGGACTGAGCCAGCGCTATCCGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAACAATTGGTTCAAACGGTCTTTTCTAAAGTCGAGCGCTTAGAGGCTTTCCCTGAATCGGGTCGCATTCCGC
CTGAACTAGAACATCTAAGTTATCGTGAAGTTGTAGTTAATCCGTGCCGCGTTTTCTATAAACAAGACGGCGACAAAGTA
TTTATTCTGTTTGTTATGCGTGCTGAGAGAGACTTGCGTAAGTTCCTACTGAGCAAGCAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9590.14 Da        Isoelectric Point: 7.3177

>AT69708 WP_088880731.1 NZ_CP018312:1277918-1278175 [Vibrio rotiferianus]
MKVELVTSLKRQATKILADLHVTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK

Download         Length: 258 bp

>AT69708 NZ_CP018312:1277918-1278175 [Vibrio rotiferianus]
ATGAAAGTAGAACTAGTTACATCACTCAAACGCCAAGCAACAAAGATCCTTGCCGATCTCCACGTCACTAAGGAACCAGT
GTTAATTACCGAACATGGTAAACCATCGGCATATCTGGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGCGA
TTCTGGAGGGGATTGCACGAGGTGAACGTGCATTAGCTGATGGTAAAGTGGTGAGTCACGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References