Detailed information of TA system TA069298

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 475086..475725
• Replicon: chromosome
• Accession: NZ_CP018260
• Organism: Acinetobacter haemolyticus strain XH900

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: C0VNL5
• Locus tag: BSR56_RS02410
• Protein ID: WP_005088316.1
• Coordinates: 475330..475725 (+)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: BSR56_RS02405
• Protein ID: WP_100833185.1
• Coordinates: 475086..475343 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSR56_RS02380	470162..470527	+	366	WP_004641032.1	50S ribosomal protein L17	-
BSR56_RS02385	470692..471189	+	498	WP_100833183.1	GNAT family N-acetyltransferase	-
BSR56_RS02390	471565..473055	+	1491	WP_075314692.1	NAD(P)/FAD-dependent oxidoreductase	-
BSR56_RS02395	473178..473675	+	498	WP_005088321.1	DUF2059 domain-containing protein	-
BSR56_RS02400	473727..474899	-	1173	WP_100833184.1	acyl-CoA dehydrogenase family protein	-
BSR56_RS02405	475086..475343	+	258	WP_100833185.1	succinate dehydrogenase assembly factor 2	Antitoxin
BSR56_RS02410	475330..475725	+	396	WP_005088316.1	hypothetical protein	Toxin
BSR56_RS02415	475936..476142	+	207	WP_171261742.1	hypothetical protein	-
BSR56_RS02420	476502..477545	+	1044	WP_100833186.1	hypothetical protein	-
BSR56_RS02425	477673..478254	+	582	WP_004641018.1	rhombosortase	-
BSR56_RS02430	478432..480642	+	2211	WP_100833187.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 16153.44 Da
• Isoelectric Point: 9.1954

>T69298 WP_005088316.1 NZ_CP018260:475330-475725 [Acinetobacter haemolyticus]
MSTADRVFVLKRSRFAFAFQLFIFIVLISLLYYLLPWFLWLVSFPLMLIAWVLLLKQPQLKHFEYLDDQLCSLCFSDEMQ
RIEQRKIRKMIDHQCYIVIYFYDSQCRPCVIWWDQLSILQWKKLRTWVKLA

Nucleotide

• Length: 396 bp

>T69298 NZ_CP018260:475330-475725 [Acinetobacter haemolyticus]
ATGTCCACGGCTGATCGTGTTTTTGTGTTGAAACGCAGTCGTTTTGCATTTGCGTTTCAACTTTTTATTTTTATCGTACT
GATCAGTTTATTGTATTACTTACTTCCTTGGTTTTTATGGCTTGTTAGCTTTCCTTTGATGCTAATTGCTTGGGTATTAT
TACTCAAACAACCTCAGCTTAAACACTTTGAATATTTAGATGATCAGCTTTGCTCCTTGTGTTTTAGTGATGAGATGCAG
AGGATCGAGCAAAGGAAAATTCGAAAAATGATCGATCATCAATGTTATATCGTCATCTATTTTTATGACTCTCAATGTCG
ACCTTGTGTGATTTGGTGGGATCAATTGTCGATTTTACAGTGGAAAAAGCTCAGAACATGGGTCAAACTTGCATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10040.45 Da
• Isoelectric Point: 4.3805

>AT69298 WP_100833185.1 NZ_CP018260:475086-475343 [Acinetobacter haemolyticus]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNCYLTADEAEKALFAELVDQEDPDLLDWFMEVGEPPRPELKAFISKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT69298 NZ_CP018260:475086-475343 [Acinetobacter haemolyticus]
ATGTCTGAAGAATTGACACTAGAAGAACGTAAAGTGATTTATCGTGCGCGTCGTGGTTTGAAAGAAATCGATGTGTATTT
TGATCCTTATGTCAAAAATTGTTATCTCACAGCAGATGAGGCTGAGAAAGCATTGTTTGCAGAGTTGGTAGATCAAGAAG
ATCCTGATTTACTGGATTGGTTCATGGAGGTGGGTGAACCTCCTCGTCCAGAGTTAAAAGCGTTTATTTCAAAATTAAAA
CAGTATGTCCACGGCTGA

Structures

Toxin

• AlphaFold DB: A0A1L6KJV0