Detailed information of TA system TA069295

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 3907004..3907626
• Replicon: chromosome
• Accession: NZ_CP018259
• Organism: Acinetobacter bereziniae strain XH901

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: BSR55_RS18390
• Protein ID: WP_100885994.1
• Coordinates: 3907004..3907399 (-)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: BSR55_RS18395
• Protein ID: WP_100885995.1
• Coordinates: 3907396..3907626 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSR55_RS18370	3902788..3903699	-	912	WP_005031233.1	SDR family oxidoreductase	-
BSR55_RS18375	3903788..3905578	-	1791	WP_100885993.1	DUF1446 domain-containing protein	-
BSR55_RS18380	3905746..3906345	+	600	WP_034708510.1	TetR/AcrR family transcriptional regulator	-
BSR55_RS18385	3906415..3906750	+	336	Protein_3543	hypothetical protein	-
BSR55_RS18390	3907004..3907399	-	396	WP_100885994.1	type II toxin-antitoxin system VapC family toxin	Toxin
BSR55_RS18395	3907396..3907626	-	231	WP_100885995.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
BSR55_RS18400	3907728..3908897	-	1170	WP_100885996.1	acyl-CoA dehydrogenase family protein	-
BSR55_RS18405	3908972..3910135	-	1164	WP_100885997.1	acyl-CoA dehydrogenase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-123)

Antitoxin

• SpoVT-AbrB domain (7-44)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 14802.22 Da
• Isoelectric Point: 6.7177

>T69295 WP_100885994.1 NZ_CP018259:c3907399-3907004 [Acinetobacter bereziniae]
VIYLLDTNICIYVINNKPAQVFEKFKQYQLGQLVISSISASELAFGVEKSGSLRNKNALDKFLAPLDILPYDENAIWHYA
KLRQTLHAKGQPIGSLDMLIAAHALALDTILVTNNMKEFERIEGLKLENWI

Nucleotide

• Length: 396 bp

>T69295 NZ_CP018259:c3907399-3907004 [Acinetobacter bereziniae]
GTGATTTACTTGCTGGATACCAATATCTGTATTTATGTTATCAATAATAAACCAGCACAGGTTTTTGAAAAATTTAAACA
ATATCAACTAGGTCAATTAGTAATTTCCAGTATTAGTGCTTCGGAGTTGGCTTTTGGGGTAGAAAAGTCTGGATCCCTTC
GAAATAAAAATGCTTTGGACAAGTTTTTAGCACCTTTAGATATTCTTCCTTATGATGAAAATGCAATTTGGCATTATGCA
AAATTAAGACAAACATTGCATGCTAAAGGACAACCCATTGGTAGCTTAGATATGTTAATCGCAGCACATGCATTAGCCTT
AGACACTATTTTAGTGACAAATAATATGAAAGAATTTGAGCGGATTGAAGGACTAAAATTAGAAAATTGGATTTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8857.21 Da
• Isoelectric Point: 4.6512

>AT69295 WP_100885995.1 NZ_CP018259:c3907626-3907396 [Acinetobacter bereziniae]
MEVAKIFQSGRSQAVRLPKAFRFEGKEVVVKHFGNGVLLLPLKNPWEIMQEAVLEFEDDFLLEREEQGVQNREELL

Nucleotide

• Length: 231 bp

>AT69295 NZ_CP018259:c3907626-3907396 [Acinetobacter bereziniae]
ATGGAAGTTGCAAAAATTTTTCAATCTGGACGTAGTCAGGCAGTTCGGTTACCTAAAGCATTTCGTTTTGAGGGAAAGGA
AGTTGTGGTTAAACATTTTGGCAACGGTGTTTTATTATTACCCTTAAAGAATCCTTGGGAAATTATGCAAGAGGCAGTAT
TGGAATTCGAAGATGATTTCCTACTAGAACGAGAAGAACAAGGTGTCCAAAATAGAGAGGAGTTATTGTGA