Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2470184..2470455 Replicon chromosome
Accession NZ_CP018245
Organism Escherichia coli strain 472

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2470222..2470325 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2470184..2470455 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFL23_RS13710 2467341..2468780 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BFL23_RS13715 2468898..2469134 + 237 WP_001295499.1 DUF1480 family protein -
BFL23_RS13720 2469239..2469430 + 192 WP_001296140.1 YebW family protein -
BFL23_RS13725 2469431..2470087 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2470184..2470455 + 272 - - Antitoxin
- 2470222..2470325 - 104 - - Toxin
BFL23_RS13735 2470483..2470824 - 342 WP_000976483.1 YebY family protein -
BFL23_RS13740 2470837..2471709 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
BFL23_RS13745 2471713..2472087 - 375 WP_000168751.1 CopC domain-containing protein YobA -
BFL23_RS13750 2472226..2472456 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BFL23_RS13755 2472558..2473214 + 657 WP_072617024.1 carbon-nitrogen hydrolase family protein -
BFL23_RS13760 2473238..2473900 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T69147 NZ_CP018245:c2470325-2470222 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT69147 NZ_CP018245:2470184-2470455 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References