Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2374498..2374769 Replicon chromosome
Accession NZ_CP018243
Organism Escherichia coli strain 350

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2374536..2374639 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2374498..2374769 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFL21_RS12950 2371655..2373094 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BFL21_RS12955 2373212..2373448 + 237 WP_001295499.1 DUF1480 family protein -
BFL21_RS12960 2373553..2373744 + 192 WP_001296140.1 YebW family protein -
BFL21_RS12965 2373745..2374401 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2374498..2374769 + 272 - - Antitoxin
- 2374536..2374639 - 104 - - Toxin
BFL21_RS12975 2374797..2375138 - 342 WP_000976483.1 YebY family protein -
BFL21_RS12980 2375151..2376023 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
BFL21_RS12985 2376027..2376401 - 375 WP_000168751.1 CopC domain-containing protein YobA -
BFL21_RS12990 2376540..2376770 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BFL21_RS12995 2376872..2377528 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
BFL21_RS13000 2377552..2378214 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T69112 NZ_CP018243:c2374639-2374536 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT69112 NZ_CP018243:2374498-2374769 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References