Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2493957..2494191 Replicon chromosome
Accession NZ_CP018237
Organism Escherichia coli strain 155

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2493958..2494061 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2493957..2494191 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFL20_RS13860 2491154..2491964 + 811 Protein_2459 recombination protein RecT -
BFL20_RS13865 2492021..2492215 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
BFL20_RS13870 2492208..2492396 + 189 WP_072612771.1 DUF1187 family protein -
- 2492214..2492392 - 179 NuclAT_0 - -
- 2492214..2492392 - 179 NuclAT_0 - -
- 2492214..2492392 - 179 NuclAT_0 - -
- 2492214..2492392 - 179 NuclAT_0 - -
BFL20_RS13875 2492503..2492784 + 282 WP_001311878.1 excisionase -
BFL20_RS13880 2492750..2493826 + 1077 WP_072612772.1 phage integrase Arm DNA-binding domain-containing protein -
- 2493957..2494191 + 235 - - Antitoxin
- 2493958..2494061 - 104 - - Toxin
BFL20_RS13890 2494219..2494560 - 342 WP_000976483.1 YebY family protein -
BFL20_RS13895 2494573..2495445 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
BFL20_RS13900 2495449..2495823 - 375 WP_000168751.1 CopC domain-containing protein YobA -
BFL20_RS13905 2495962..2496192 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BFL20_RS13910 2496294..2496950 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
BFL20_RS13915 2496974..2497636 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T68985 NZ_CP018237:c2494061-2493958 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTACTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT68985 NZ_CP018237:2493957-2494191 [Escherichia coli]
TAAAAAAAGACCGAGTACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References