Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 826050..826852 Replicon chromosome
Accession NZ_CP018221
Organism Tardibacter chloracetimidivorans strain JJ-A5

Toxin (Protein)


Gene name TacT3 Uniprot ID A0A1L3ZSL3
Locus tag BSL82_RS04250 Protein ID WP_072596182.1
Coordinates 826050..826577 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A1L3ZSM3
Locus tag BSL82_RS04255 Protein ID WP_031290683.1
Coordinates 826574..826852 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSL82_RS04235 824495..824896 - 402 Protein_832 hypothetical protein -
BSL82_RS04250 826050..826577 - 528 WP_072596182.1 GNAT family N-acetyltransferase Toxin
BSL82_RS04255 826574..826852 - 279 WP_031290683.1 DUF1778 domain-containing protein Antitoxin
BSL82_RS04260 827103..827864 - 762 WP_158010677.1 LuxR family transcriptional regulator -
BSL82_RS04265 827960..828727 - 768 WP_007686288.1 IS21-like element ISSsp5 family helper ATPase IstB -
BSL82_RS04270 828724..830217 - 1494 WP_083579292.1 IS21 family transposase -
BSL82_RS04275 830510..831262 + 753 WP_072596184.1 glucose 1-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 802479..947156 144677


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(7-89)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19094.71 Da        Isoelectric Point: 7.0510

>T68951 WP_072596182.1 NZ_CP018221:c826577-826050 [Tardibacter chloracetimidivorans]
MTLPSWHEEAISKAHDRASFDCGDNDLNVYLQRYARQSHEAGGAKTFLAIDDTDNKTVLGFYSIAPGSMDHADTPELARR
GLARHEVPGFRLARLATDVRVQGKGLGGQLLGAIGRRCIRVAAEVGGVMLIIDAKNERAAEWYASYGAIPLHDKPLTLIL
PFATLERELRAAGQI

Download         Length: 528 bp

>T68951 NZ_CP018221:c826577-826050 [Tardibacter chloracetimidivorans]
ATGACCCTTCCTTCATGGCACGAGGAAGCGATTTCGAAAGCGCATGATCGGGCTTCATTCGACTGCGGCGACAATGATCT
GAACGTCTACTTGCAGCGCTATGCGCGGCAAAGCCATGAGGCAGGCGGGGCGAAGACGTTCCTCGCCATCGACGACACCG
ACAACAAGACGGTTCTCGGCTTTTACAGCATCGCTCCGGGCAGCATGGATCATGCGGATACGCCAGAACTGGCGAGGCGA
GGACTCGCCAGGCATGAGGTGCCGGGCTTCCGGCTCGCGCGGCTTGCGACGGATGTGCGTGTGCAGGGGAAAGGACTCGG
GGGTCAGCTCCTGGGCGCGATCGGGCGCAGATGCATTCGCGTCGCGGCCGAGGTCGGCGGGGTTATGCTGATCATCGACG
CCAAAAACGAGCGCGCTGCCGAGTGGTATGCGAGCTACGGCGCAATTCCGCTGCACGACAAACCGCTGACACTCATATTG
CCTTTTGCGACACTCGAACGTGAATTGAGAGCTGCTGGCCAGATCTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10254.96 Da        Isoelectric Point: 10.5767

>AT68951 WP_031290683.1 NZ_CP018221:c826852-826574 [Tardibacter chloracetimidivorans]
MPRAVVEDNRRMSLRIRPEQKALLARAAALKHTDLTTFVTRSALREAENVIEEAERTKLSERDSLLVLDLLENPPPANAK
LRAAIAAMPKLA

Download         Length: 279 bp

>AT68951 NZ_CP018221:c826852-826574 [Tardibacter chloracetimidivorans]
ATGCCGCGAGCAGTAGTGGAAGACAACAGGCGCATGAGCCTGCGCATTCGGCCTGAGCAAAAGGCTTTGCTCGCCCGGGC
GGCTGCGCTCAAGCACACCGATCTCACGACCTTTGTAACACGTTCGGCGCTGCGTGAGGCCGAGAACGTGATCGAAGAGG
CGGAGCGGACGAAGCTGAGCGAGAGAGACAGCCTGCTCGTTCTTGATCTGCTCGAGAACCCGCCGCCGGCGAATGCGAAA
CTGCGCGCTGCCATCGCTGCGATGCCGAAGTTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L3ZSL3

Antitoxin

Source ID Structure
AlphaFold DB A0A1L3ZSM3

References