Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2660177..2660448 Replicon chromosome
Accession NZ_CP018206
Organism Escherichia coli strain MRSN346647

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2660215..2660318 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2660177..2660448 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSZ13_RS13680 2657334..2658773 + 1440 WP_049068043.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BSZ13_RS13685 2658891..2659127 + 237 WP_001295499.1 DUF1480 family protein -
BSZ13_RS13690 2659232..2659423 + 192 WP_001296140.1 YebW family protein -
BSZ13_RS13695 2659424..2660080 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 2660177..2660448 + 272 - - Antitoxin
- 2660215..2660318 - 104 - - Toxin
BSZ13_RS13710 2660476..2660817 - 342 WP_000976472.1 YebY family protein -
BSZ13_RS13715 2660830..2661702 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
BSZ13_RS13720 2661706..2662080 - 375 WP_000168747.1 CopC domain-containing protein YobA -
BSZ13_RS13725 2662219..2662449 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BSZ13_RS13730 2662551..2663207 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
BSZ13_RS13735 2663231..2663893 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2644337..2669621 25284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T68932 NZ_CP018206:c2660318-2660215 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT68932 NZ_CP018206:2660177-2660448 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References