Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 11960..12407 Replicon plasmid p9853_B
Accession NZ_CP018204
Organism Pseudomonas syringae pv. actinidiae ICMP 9853

Toxin (Protein)


Gene name relE Uniprot ID A0A3M4C5F0
Locus tag JN853_RS31400 Protein ID WP_003348606.1
Coordinates 11960..12232 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E7PTW6
Locus tag JN853_RS31405 Protein ID WP_003381808.1
Coordinates 12222..12407 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN853_RS33985 7306..7710 - 405 WP_025991968.1 hypothetical protein -
JN853_RS33990 8228..8500 + 273 Protein_7 DNA polymerase V subunit UmuC -
JN853_RS33995 8804..9320 + 517 Protein_8 DUF4113 domain-containing protein -
JN853_RS31385 9643..10050 - 408 WP_080033422.1 hypothetical protein -
JN853_RS32525 10126..11705 + 1580 WP_085991147.1 IS3-like element ISPsy31 family transposase -
JN853_RS31400 11960..12232 - 273 WP_003348606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JN853_RS31405 12222..12407 - 186 WP_003381808.1 hypothetical protein Antitoxin
JN853_RS31410 12458..12736 - 279 WP_003381807.1 hypothetical protein -
JN853_RS31415 12831..13466 - 636 WP_020304372.1 recombinase family protein -
JN853_RS31420 13765..14397 + 633 WP_003381804.1 ParA family protein -
JN853_RS31425 14433..14687 + 255 WP_003381801.1 hypothetical protein -
JN853_RS31435 15274..15894 + 621 WP_005769724.1 recombinase family protein -
JN853_RS31440 15913..16209 - 297 WP_025992726.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..32947 32947


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10199.67 Da        Isoelectric Point: 5.0749

>T68896 WP_003348606.1 NZ_CP018204:c12232-11960 [Pseudomonas syringae pv. actinidiae ICMP 9853]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIL
DVLHARQEYP

Download         Length: 273 bp

>T68896 NZ_CP018204:c12232-11960 [Pseudomonas syringae pv. actinidiae ICMP 9853]
GTGCTAGTTGAGTGGCTTCCACAAGCTTTGGAGGCACTGGAGGAAATCGCCGGCTACCTAGCCGAGCGCAACCCTTATGC
TGCCGAGCAGATGCAGGCTACCCTTGAGGCCACGGTCGAGGCTCTCCCCCTGCACCCTTACATCCACCGTCCCGGCCGTG
TTCCAGGAACGCGCGAAGCGGTTGTGCATCCCAACTACCTGGTTGTCTACCGCGTCGGTACAGAGCGCATCAGCATCTTG
GACGTCCTGCACGCCCGCCAAGAGTACCCCTAG

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7296.25 Da        Isoelectric Point: 8.7721

>AT68896 WP_003381808.1 NZ_CP018204:c12407-12222 [Pseudomonas syringae pv. actinidiae ICMP 9853]
MSIQLDPRVSEFETQEQADNYDRWFRLRIERSLADPRPPVPHDEAMARVRAMIEAKRRRAS

Download         Length: 186 bp

>AT68896 NZ_CP018204:c12407-12222 [Pseudomonas syringae pv. actinidiae ICMP 9853]
ATGAGCATTCAACTTGACCCTCGCGTCTCGGAGTTCGAGACCCAGGAACAGGCCGACAATTACGACCGTTGGTTTCGCCT
GCGTATCGAGCGCAGTTTGGCCGATCCGCGTCCACCCGTGCCGCACGATGAAGCAATGGCTCGCGTCAGAGCCATGATCG
AGGCAAAGCGCCGCCGTGCTAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M4C5F0

Antitoxin

Source ID Structure
AlphaFold DB A0A2V0QZQ1

References