68894

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4809016..4809412 Replicon chromosome
Accession NZ_CP018202
Organism Pseudomonas syringae pv. actinidiae ICMP 9853

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag JN853_RS33380 Protein ID WP_003382608.1
Coordinates 4809251..4809412 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2V0QH46
Locus tag JN853_RS23325 Protein ID WP_003382609.1
Coordinates 4809016..4809261 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN853_RS23320 4804933..4808844 - 3912 WP_003382610.1 ATP-dependent RNA helicase HrpA -
JN853_RS23325 4809016..4809261 + 246 WP_003382609.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JN853_RS33380 4809251..4809412 + 162 WP_003382608.1 hypothetical protein Toxin
JN853_RS33385 4809413..4809541 + 129 WP_020304092.1 type II toxin-antitoxin system RelE/ParE family toxin -
JN853_RS23335 4809668..4811359 - 1692 WP_003382607.1 long-chain-fatty-acid--CoA ligase FadD1 -
JN853_RS23340 4811714..4813402 - 1689 WP_003382606.1 long-chain-fatty-acid--CoA ligase FadD2 -
JN853_RS23350 4813798..4814268 + 471 WP_003382605.1 MaoC family dehydratase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(9-69)


Sequences


Toxin        


Download         Length: 54 a.a.        Molecular weight: 6207.31 Da        Isoelectric Point: 10.1505

>T68894 WP_003382608.1 NZ_CP018202:4809251-4809412 [Pseudomonas syringae pv. actinidiae ICMP 9853]
MTFKLEFLPSALKEWKKLGHTVSDQFKKKLLERLELPRNAGDALHGMPDHYKI

Download         Length: 162 bp

>T68894 NZ_CP018202:4809251-4809412 [Pseudomonas syringae pv. actinidiae ICMP 9853]
ATGACCTTTAAGCTCGAGTTTCTGCCTTCAGCCCTGAAGGAGTGGAAAAAACTGGGGCATACCGTTAGTGATCAATTCAA
GAAAAAGCTTTTGGAGCGGCTCGAATTACCTCGAAATGCGGGCGATGCGCTGCATGGCATGCCCGATCACTACAAAATCT
AG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8945.31 Da        Isoelectric Point: 4.5349

>AT68894 WP_003382609.1 NZ_CP018202:4809016-4809261 [Pseudomonas syringae pv. actinidiae ICMP 9853]
MQNVFADIEVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLADLIKSRQHEKPVSVDIHD
L

Download         Length: 246 bp

>AT68894 NZ_CP018202:4809016-4809261 [Pseudomonas syringae pv. actinidiae ICMP 9853]
ATGCAAAATGTCTTTGCGGACATCGAGGTCAGCGTCTCTGAGCTGAAGAAAAACCCGTCAGCCGTCCTGAGCGGCGCACA
AGGCTTGCCCGTCGCAGTACTCAATCACAATAAAGTCATGGGCTACATGGTGCCTGCCGAGGTGTTTGAAGCAATGATGG
AGCGCCTTGATGACCTCGATCTGGCCGACCTGATCAAATCCAGGCAACATGAAAAGCCGGTATCGGTAGATATACATGAC
CTTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A2V0QH46

References