Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 3622966..3623346 Replicon chromosome
Accession NZ_CP018171
Organism Mesorhizobium oceanicum strain B7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSQ44_RS17745 Protein ID WP_072606474.1
Coordinates 3622966..3623106 (-) Length 47 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag BSQ44_RS17750 Protein ID WP_072608134.1
Coordinates 3623119..3623346 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSQ44_RS17725 3618043..3620067 + 2025 WP_072606470.1 phenylacetic acid degradation bifunctional protein PaaZ -
BSQ44_RS17730 3620073..3621257 - 1185 WP_083534796.1 multidrug effflux MFS transporter -
BSQ44_RS17735 3621254..3622324 - 1071 WP_072606472.1 3-carboxy-cis,cis-muconate cycloisomerase -
BSQ44_RS17740 3622340..3622951 - 612 WP_072606473.1 protocatechuate 3,4-dioxygenase subunit alpha -
BSQ44_RS17745 3622966..3623106 - 141 WP_072606474.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSQ44_RS17750 3623119..3623346 - 228 WP_072608134.1 ribbon-helix-helix protein, CopG family Antitoxin
BSQ44_RS17755 3623409..3624167 - 759 WP_072606475.1 protocatechuate 3,4-dioxygenase subunit beta -
BSQ44_RS17760 3624164..3624565 - 402 WP_072608135.1 4-carboxymuconolactone decarboxylase -
BSQ44_RS17765 3624711..3625883 - 1173 WP_072606476.1 4-hydroxybenzoate 3-monooxygenase -
BSQ44_RS17770 3625999..3626880 + 882 WP_072608136.1 helix-turn-helix domain-containing protein -
BSQ44_RS17775 3626985..3628010 - 1026 WP_072606477.1 fatty acid desaturase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-45)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5349.16 Da        Isoelectric Point: 7.1605

>T68867 WP_072606474.1 NZ_CP018171:c3623106-3622966 [Mesorhizobium oceanicum]
VAAALHASLENYWSYRVGDYRLICEIKDQKLVVLVVDIGHRSDIYR

Download         Length: 141 bp

>T68867 NZ_CP018171:c3623106-3622966 [Mesorhizobium oceanicum]
GTGGCGGCGGCGCTTCACGCCTCGCTTGAAAACTACTGGTCCTACCGCGTGGGCGACTACCGCCTCATCTGCGAGATAAA
GGACCAGAAACTCGTCGTCCTGGTCGTGGATATCGGCCATCGATCGGACATCTATCGCTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8690.71 Da        Isoelectric Point: 4.8359

>AT68867 WP_072608134.1 NZ_CP018171:c3623346-3623119 [Mesorhizobium oceanicum]
MPYSIRLKPGIEARLDALAARTGYSKAYHLRELVANGLDDLEAYYTAVEVSERIRRGEERTYTLDEVRRDLGWDD

Download         Length: 228 bp

>AT68867 NZ_CP018171:c3623346-3623119 [Mesorhizobium oceanicum]
ATGCCGTACAGCATTCGACTCAAGCCCGGAATCGAAGCCCGACTGGACGCGCTGGCTGCCAGGACCGGTTACTCCAAGGC
CTACCACCTGCGCGAGCTGGTCGCGAACGGGCTGGATGACTTGGAGGCCTACTACACCGCGGTAGAGGTGTCAGAACGCA
TCCGTCGCGGAGAAGAGAGGACCTACACTCTGGATGAAGTAAGACGCGACCTCGGCTGGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References