Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 3396873..3397376 | Replicon | chromosome |
| Accession | NZ_CP018171 | ||
| Organism | Mesorhizobium oceanicum strain B7 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | - |
| Locus tag | BSQ44_RS16625 | Protein ID | WP_210187880.1 |
| Coordinates | 3396873..3397097 (-) | Length | 75 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | A0A1L3STS1 |
| Locus tag | BSQ44_RS16630 | Protein ID | WP_072606154.1 |
| Coordinates | 3397143..3397376 (-) | Length | 78 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BSQ44_RS16605 | 3393182..3393799 | - | 618 | WP_072608114.1 | MOSC domain-containing protein | - |
| BSQ44_RS16610 | 3393814..3394935 | - | 1122 | WP_072606146.1 | beta-ketoacyl-ACP synthase III | - |
| BSQ44_RS16615 | 3395153..3395938 | - | 786 | WP_072606148.1 | trans-aconitate 2-methyltransferase | - |
| BSQ44_RS16620 | 3396136..3396507 | - | 372 | WP_072606150.1 | hypothetical protein | - |
| BSQ44_RS16625 | 3396873..3397097 | - | 225 | WP_210187880.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| BSQ44_RS16630 | 3397143..3397376 | - | 234 | WP_072606154.1 | TraY domain-containing protein | Antitoxin |
| BSQ44_RS16635 | 3397437..3399086 | - | 1650 | WP_072606156.1 | energy-dependent translational throttle protein EttA | - |
| BSQ44_RS16640 | 3399320..3401332 | + | 2013 | WP_072606158.1 | DEAD/DEAH box helicase | - |
| BSQ44_RS16645 | 3401620..3402306 | + | 687 | WP_072606160.1 | SDR family NAD(P)-dependent oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 75 a.a. Molecular weight: 8695.02 Da Isoelectric Point: 10.6044
>T68866 WP_210187880.1 NZ_CP018171:c3397097-3396873 [Mesorhizobium oceanicum]
MKRIGSVDRERIARFIRDRIVNRSDPREIGEALAGPFSGYWKYRIGDYRIIAAIEDEVVTVVVVRIGNRREVYR
MKRIGSVDRERIARFIRDRIVNRSDPREIGEALAGPFSGYWKYRIGDYRIIAAIEDEVVTVVVVRIGNRREVYR
Download Length: 225 bp
>T68866 NZ_CP018171:c3397097-3396873 [Mesorhizobium oceanicum]
ATGAAGCGGATCGGATCAGTTGACCGCGAAAGGATCGCCCGCTTCATCCGCGACCGTATCGTCAACCGGTCCGACCCACG
CGAGATCGGCGAAGCGCTTGCCGGCCCATTCTCCGGCTACTGGAAATATCGCATCGGCGACTACCGCATAATCGCCGCGA
TCGAGGACGAGGTCGTCACAGTCGTCGTCGTGCGGATTGGCAATCGGCGGGAAGTGTATCGGTAA
ATGAAGCGGATCGGATCAGTTGACCGCGAAAGGATCGCCCGCTTCATCCGCGACCGTATCGTCAACCGGTCCGACCCACG
CGAGATCGGCGAAGCGCTTGCCGGCCCATTCTCCGGCTACTGGAAATATCGCATCGGCGACTACCGCATAATCGCCGCGA
TCGAGGACGAGGTCGTCACAGTCGTCGTCGTGCGGATTGGCAATCGGCGGGAAGTGTATCGGTAA
Antitoxin
Download Length: 78 a.a. Molecular weight: 9084.34 Da Isoelectric Point: 4.5626
>AT68866 WP_072606154.1 NZ_CP018171:c3397376-3397143 [Mesorhizobium oceanicum]
MLALRLPPEVEKRLDDLARKTGRTKSFYAREAILEHLADLEDAYLAEQRMRDNPQFVEFEDVLRELDIDLDRPAQKV
MLALRLPPEVEKRLDDLARKTGRTKSFYAREAILEHLADLEDAYLAEQRMRDNPQFVEFEDVLRELDIDLDRPAQKV
Download Length: 234 bp
>AT68866 NZ_CP018171:c3397376-3397143 [Mesorhizobium oceanicum]
ATGCTCGCACTGAGATTACCGCCTGAAGTCGAGAAACGTCTGGACGATCTGGCCCGCAAGACTGGCCGGACCAAGAGCTT
TTACGCGCGCGAGGCGATACTCGAACATCTGGCTGATCTCGAAGACGCCTATCTCGCCGAACAGCGCATGCGCGACAATC
CGCAATTCGTGGAGTTCGAGGACGTCCTGCGCGAACTGGATATTGATCTCGACCGGCCGGCCCAAAAGGTCTGA
ATGCTCGCACTGAGATTACCGCCTGAAGTCGAGAAACGTCTGGACGATCTGGCCCGCAAGACTGGCCGGACCAAGAGCTT
TTACGCGCGCGAGGCGATACTCGAACATCTGGCTGATCTCGAAGACGCCTATCTCGCCGAACAGCGCATGCGCGACAATC
CGCAATTCGTGGAGTTCGAGGACGTCCTGCGCGAACTGGATATTGATCTCGACCGGCCGGCCCAAAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|