Detailed information of TA system TA068857

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 449217..449870
• Replicon: chromosome
• Accession: NZ_CP018143
• Organism: Acinetobacter baumannii strain HRAB-85

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: BKJ37_RS02175
• Protein ID: WP_000607077.1
• Coordinates: 449481..449870 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: BKJ37_RS02170
• Protein ID: WP_001288210.1
• Coordinates: 449217..449474 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BKJ37_RS02150	444733..445740	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
BKJ37_RS02155	445759..446136	+	378	WP_001216380.1	50S ribosomal protein L17	-
BKJ37_RS02160	446318..447808	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
BKJ37_RS02165	447857..449029	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
BKJ37_RS02170	449217..449474	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
BKJ37_RS02175	449481..449870	+	390	WP_000607077.1	membrane protein	Toxin
BKJ37_RS02180	450640..451725	+	1086	WP_000049106.1	hypothetical protein	-
BKJ37_RS02185	451803..452369	+	567	WP_000651538.1	rhombosortase	-
BKJ37_RS02190	452557..454752	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T68857 WP_000607077.1 NZ_CP018143:449481-449870 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T68857 NZ_CP018143:449481-449870 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT68857 WP_001288210.1 NZ_CP018143:449217-449474 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT68857 NZ_CP018143:449217-449474 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7