Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2021362..2021507 | Replicon | chromosome |
| Accession | NZ_CP018140 | ||
| Organism | Klebsiella pneumoniae strain Kp_Goe_822579 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2021398..2021500 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2021362..2021507 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BB744_RS10220 | 2016492..2018552 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| BB744_RS10230 | 2018556..2019215 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| BB744_RS10235 | 2019294..2019524 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| BB744_RS10240 | 2019637..2020011 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| BB744_RS10245 | 2020015..2020884 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| BB744_RS10250 | 2020901..2021239 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2021362..2021507 | - | 146 | - | - | Antitoxin |
| - | 2021398..2021500 | + | 103 | - | - | Toxin |
| BB744_RS32200 | 2021876..2022019 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| BB744_RS10265 | 2022124..2023092 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| BB744_RS10270 | 2023249..2023902 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| BB744_RS10275 | 2023899..2024090 | - | 192 | WP_002911395.1 | YebW family protein | - |
| BB744_RS10280 | 2024188..2024427 | - | 240 | WP_002911393.1 | YebV family protein | - |
| BB744_RS10285 | 2024543..2025976 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T68843 NZ_CP018140:2021398-2021500 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT68843 NZ_CP018140:c2021507-2021362 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
