Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1843750..1844351 Replicon chromosome
Accession NZ_CP018101
Organism Delftia sp. HK171

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BO996_RS08315 Protein ID WP_071954479.1
Coordinates 1844055..1844351 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I0JJN0
Locus tag BO996_RS08310 Protein ID WP_063327131.1
Coordinates 1843750..1844058 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BO996_RS08290 1838750..1839439 + 690 WP_043783264.1 hypothetical protein -
BO996_RS08295 1839626..1840240 + 615 WP_071954476.1 SCO family protein -
BO996_RS08300 1840402..1841979 + 1578 WP_071954477.1 methyl-accepting chemotaxis protein -
BO996_RS08305 1841976..1843733 + 1758 WP_071954478.1 GGDEF domain-containing phosphodiesterase -
BO996_RS08310 1843750..1844058 - 309 WP_063327131.1 putative addiction module antidote protein Antitoxin
BO996_RS08315 1844055..1844351 - 297 WP_071954479.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BO996_RS08320 1844399..1845082 - 684 WP_071954480.1 Crp/Fnr family transcriptional regulator -
BO996_RS08325 1845318..1846295 - 978 WP_071954481.1 hypothetical protein -
BO996_RS08330 1846295..1848247 - 1953 WP_071954482.1 StlD/DarB family beta-ketosynthase -
BO996_RS08335 1848263..1849198 - 936 WP_071954483.1 fatty acid desaturase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11227.03 Da        Isoelectric Point: 8.9887

>T68693 WP_071954479.1 NZ_CP018101:c1844351-1844055 [Delftia sp. HK171]
MYSVIETETFADWVDSIRDMPTRICLRRRLGKAMRGNLGDVKSVGEGLWEMREFFGPGWRMYYIQRDHVLIVMLGGGDKS
SQAQDIAAARAMAREIKL

Download         Length: 297 bp

>T68693 NZ_CP018101:c1844351-1844055 [Delftia sp. HK171]
ATGTACAGCGTCATCGAAACCGAGACGTTTGCTGATTGGGTAGACAGCATTCGTGACATGCCAACTCGTATCTGCCTGCG
TCGTCGCCTGGGCAAAGCCATGCGCGGAAACCTGGGAGACGTGAAATCCGTTGGCGAGGGCCTATGGGAGATGCGCGAGT
TTTTCGGGCCAGGTTGGCGCATGTACTACATCCAACGCGATCATGTTCTGATCGTGATGCTTGGCGGCGGAGACAAGTCC
AGCCAGGCACAGGACATTGCTGCGGCCAGGGCGATGGCCAGGGAGATCAAGCTATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11135.63 Da        Isoelectric Point: 4.6151

>AT68693 WP_063327131.1 NZ_CP018101:c1844058-1843750 [Delftia sp. HK171]
MSNIKMRPFDMANYLGTEEEIVEYLRQALEDNDPAELAAALGDIARARGMTQLARDTGLSRESLYKSLSGERAPSSETLF
KVIQAMGFRLTIAPAASQQPAA

Download         Length: 309 bp

>AT68693 NZ_CP018101:c1844058-1843750 [Delftia sp. HK171]
ATGAGCAACATCAAGATGCGGCCATTCGACATGGCCAACTACCTCGGCACCGAAGAGGAAATCGTGGAGTACCTGCGCCA
GGCGCTGGAAGACAACGATCCGGCCGAACTGGCTGCGGCGCTGGGCGACATCGCACGCGCGCGCGGCATGACTCAGCTCG
CTCGCGACACCGGACTTTCTCGGGAAAGCCTCTACAAAAGCCTGTCTGGCGAACGGGCGCCCAGTTCCGAGACGCTGTTC
AAGGTGATTCAGGCCATGGGCTTCAGGCTCACCATCGCTCCTGCCGCATCGCAGCAGCCAGCAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References