Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1812740..1813371 Replicon chromosome
Accession NZ_CP018101
Organism Delftia sp. HK171

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BO996_RS08165 Protein ID WP_071954465.1
Coordinates 1812970..1813371 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BO996_RS08160 Protein ID WP_071954464.1
Coordinates 1812740..1812973 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BO996_RS08130 1807759..1807983 - 225 WP_016453212.1 hypothetical protein -
BO996_RS08135 1808005..1808628 - 624 WP_071954461.1 glutathione transferase -
BO996_RS29395 1808738..1809586 - 849 WP_198041274.1 hypothetical protein -
BO996_RS08145 1809890..1811227 + 1338 WP_065346316.1 methyl-accepting chemotaxis protein -
BO996_RS08150 1811240..1811908 - 669 WP_071954462.1 hypothetical protein -
BO996_RS08155 1812041..1812583 + 543 WP_071954463.1 helix-turn-helix domain-containing protein -
BO996_RS08160 1812740..1812973 + 234 WP_071954464.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BO996_RS08165 1812970..1813371 + 402 WP_071954465.1 type II toxin-antitoxin system VapC family toxin Toxin
BO996_RS08175 1813814..1818136 - 4323 WP_071954466.1 translocation/assembly module TamB domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

SpoVT-AbrB domain

(7-27)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14458.81 Da        Isoelectric Point: 5.8323

>T68692 WP_071954465.1 NZ_CP018101:1812970-1813371 [Delftia sp. HK171]
MILLDTNICIYIINAKPPEVLARFQQYRMGEVGLCSVVAAELAFGVAKGGSARNRQALEMFLAPLTILPFDEAAVWAYGD
LRADLERRGSPIGALDTMIAAHALSQRALLVTNNTREFAKVPGLQLDNWAVAT

Download         Length: 402 bp

>T68692 NZ_CP018101:1812970-1813371 [Delftia sp. HK171]
ATGATCCTGCTCGACACCAACATCTGCATCTACATCATCAATGCCAAGCCCCCGGAGGTGCTGGCCCGATTTCAGCAGTA
CCGCATGGGCGAGGTGGGATTGTGCAGCGTGGTTGCTGCCGAACTGGCCTTTGGCGTGGCCAAAGGCGGCTCGGCCCGTA
ACCGCCAGGCCCTGGAGATGTTTCTCGCCCCGCTCACCATCCTCCCGTTTGACGAGGCGGCCGTGTGGGCCTATGGCGAC
CTGCGTGCCGATCTGGAGCGTCGAGGCAGTCCCATAGGCGCGCTTGACACCATGATCGCTGCCCACGCCCTCAGTCAGCG
GGCCCTGCTGGTCACCAACAACACCCGCGAATTCGCCAAGGTGCCCGGCCTGCAGTTGGACAACTGGGCTGTCGCTACCT
GA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8684.75 Da        Isoelectric Point: 4.6855

>AT68692 WP_071954464.1 NZ_CP018101:1812740-1812973 [Delftia sp. HK171]
MDTARLFQSGRSQAVRLPKEYRFTGTEVVVKHFGNGVLLLPADDPWQTLQAGLAQFEPGFVLEREQPDAQQRDEISP

Download         Length: 234 bp

>AT68692 NZ_CP018101:1812740-1812973 [Delftia sp. HK171]
ATGGACACCGCACGCCTTTTCCAATCCGGCCGCAGTCAAGCCGTGCGGCTGCCCAAGGAATACCGTTTCACGGGCACTGA
AGTCGTGGTGAAGCACTTCGGCAACGGCGTGTTGCTGCTGCCCGCAGACGACCCTTGGCAAACACTGCAAGCCGGGCTGG
CTCAGTTTGAACCGGGCTTTGTGCTCGAGCGCGAGCAGCCTGATGCCCAGCAGCGGGACGAGATCAGCCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References